Home Cosmetic Science Talk Formulating Advanced Questions Best online resource describing individual preservatives and efficacy?

  • Best online resource describing individual preservatives and efficacy?

    Posted by suswang8 on December 12, 2021 at 5:49 pm

    I seem to remember stumbling upon a Web site in which several major (natural-ish) preservatives (e.g., phenoxyethanol, potassium sorbate, etc.) were listed, along with an indicator of how effective each was against bacteria (gram +/-), fungus, and yeast.  Does anyone know where this might be housed?  Thank you.

    OldPerry replied 2 years, 11 months ago 9 Members · 23 Replies
  • 23 Replies
  • PhilGeis

    Member
    December 13, 2021 at 10:39 am
  • CedarS

    Member
    December 13, 2021 at 1:08 pm

    I just came across this link today, not sure of the source. Preservatives for Cosmetics: Chemistries & Selection Tips (specialchem.com)

  • Microformulation

    Member
    December 13, 2021 at 1:12 pm

    This is a useful tool. It will of course recommend a Lonza product, but you should be able to find similar products in just about everyone’s preservative lines. https://microbialmanagement.arxada.com/Apps/FormulaProtect

  • ozgirl

    Member
    December 13, 2021 at 10:45 pm
  • vitalys

    Member
    December 14, 2021 at 4:21 pm

    @PhilGeis You shared just an invaluable book, I would say literally a text book. I think anyone in the world of cosmetic formulating should read it and learn from cover to cover. 

  • PhilGeis

    Member
    December 14, 2021 at 5:41 pm

    There is a 3rd ed (2020) that includes more info - natural and multifunctional preservatives/preservation, detailed manufacturing etc. but it’s kinda pricey.

    https://www.amazon.com/Cosmetic-Microbiology-Practical-Philip-Geis/dp/1138732915/ref=sr_1_2?keywords=Geis+cosmetic+microbiology&qid=1639503581&sr=8-2

  • vitalys

    Member
    December 14, 2021 at 6:03 pm

    @PhilGeis Yes, it is but this book can not be inexpensive. I have read 3d edition too

  • Abdullah

    Member
    December 20, 2021 at 12:36 pm

    @vitalys do you have the PDF of 3d edition? 

  • vitalys

    Member
    December 20, 2021 at 3:18 pm

    No, I have got a book

  • Abdullah

    Member
    December 20, 2021 at 3:39 pm

    @vitalys ok 
    Can you take picture that what that book has said about these preservatives

    Formalin
    Hydroxyacetophenone
    Glyceryl Caprylate

  • vitalys

    Member
    December 20, 2021 at 3:50 pm

    @Abdullah Sorry, I don’t think it is ethically correct. You may ask an editor of this book, @PhilGeis about it directly. The book is also available to purchase or order. 

  • PhilGeis

    Member
    December 20, 2021 at 3:57 pm

    Right - not legally either.

  • Abdullah

    Member
    December 20, 2021 at 4:10 pm

    vitalys said:

    @Abdullah Sorry, I don’t think it is ethically correct. You may ask an editor of this book, @PhilGeis about it directly. The book is also available to purchase or order. 

    WOW 
    That is very fortunate that the author(Philip A. Geis) is PhilGeis. I would have ask him directly if I knew that. 

    The problem is i am in Afghanistan and can’t purchase online because of recent problems with banks in our country for now. 

    @PhilGeis any comments on hydroxyacetophenone and glyceryl Caprylate.

    I like hydroxyacetophenone for for leave on Products because of the claims it has and glyceryl Caprylate in shampoo because i am using decyl Glucoside, phenoxyethanol and Amodimethicone and without glyceryl Caprylate it is very hard to get enough viscosity. But am not sure how helpful they would be for preservation

  • PhilGeis

    Member
    December 20, 2021 at 5:20 pm

    I’ve never used hydroxyacetophenone and not aware of any significant data that supports it as preservative. 
    Glyceryl caprylate.  Too susceptible to microbial esterases - and pseudomonads have plenty. 
    So don’t think either will help much for preservation. 

    I know you asked about formnaldehyde releasers - can you use those?

  • Abdullah

    Member
    December 20, 2021 at 5:33 pm

    PhilGeis said:

    I’ve never used hydroxyacetophenone and not aware of any significant data that supports it as preservative. 
    Glyceryl caprylate.  Too susceptible to microbial esterases - and pseudomonads have plenty. 
    So don’t think either will help much for preservation. 

    I know you asked about formnaldehyde releasers - can you use those?

    Yes I can

  • PhilGeis

    Member
    December 20, 2021 at 5:55 pm

    I sure would.  Add EDTA and maybe benzoic acid.  If no stability issues - I think you’d do well.
    Are you making it yourself?

  • ngarayeva001

    Member
    December 21, 2021 at 1:22 am

    PhilGeis said:

    Thank you @PhilGeis for sharing your book. This is incredibly nice of you. The table 7.3 is a treasure! 

  • Abdullah

    Member
    December 21, 2021 at 1:32 am

    PhilGeis said:

    I sure would.  Add EDTA and maybe benzoic acid.  If no stability issues - I think you’d do well.
    Are you making it yourself?

    Thanks 
    Yes i make the products myself. 

    As i am importing almost all the ingredients i use from another countries, i have to purchase in large quantities otherwise the shipping cost would be too much. 

    Currently i have some preservatives that i have to use, when they are finished i have plan to use DMDM hydantoin both is shampoo and lotions. 

  • suswang8

    Member
    December 22, 2021 at 4:35 pm

    Hi, all.
    I think I had actually been thinking of this one:
    https://www.olionatura.de/rohstofftabellen/konservierertabelle.php

    but there are a few ones “missing,” such as phenethyl alcohol.  Either way, still a great, concise resource for those who are natural-focused.

  • PhilGeis

    Member
    December 23, 2021 at 11:08 am

    suswang8 said:

    Hi, all.
    I think I had actually been thinking of this one:
    https://www.olionatura.de/rohstofftabellen/konservierertabelle.php

    but there are a few ones “missing,” such as phenethyl alcohol.  Either way, still a great, concise resource for those who are natural-focused.

    Most are “natural”: only by the Ecocert/COSMOS “credentialing”.  Be cautious of all incl penethyl alcohol.  It can partition into packaging material.

  • suswang8

    Member
    December 23, 2021 at 10:47 pm

    Is the penetration into packaging your main concern, or you have others (including for phenethyl alcohol)?

  • PhilGeis

    Member
    December 24, 2021 at 11:50 am

    Phenethyl (Rose ether) has a rose odor that may clash with perfume.  Not on directives and  not that effective - certainly < phenoxy.   
    None are that great - esp. in a shampoo/conditioner context - and very few on directives (odd for a German publication).  You’ll find little safety data for many. 

    Ferment Leucidal is vey weak abnd reportedly adulterated ala GSE https://pubs.acs.org/doi/abs/10.1021/jf5063588.

    Ethanol demands 20%. Lesser levels are not ‘sehr gut” any more than the rest of those with this silliness.

    One combination I know is effective benzyl alcohol/benzoate is labeled limited (small)

    Magnolia extract like “Parfum” is another uncharacterized/ uncontrolled magic potion.

    Glyeryl caprylate is pseudomonas ester food.

    Combined organic acids are just that - organic acids - none is sehr gut.

  • OldPerry

    Member
    December 24, 2021 at 7:42 pm

    Leucidal always cracks me up.

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