Home Cosmetic Science Talk Formulating Azelaic acid 10% and urea 10%+

  • Azelaic acid 10% and urea 10%+

    Posted by Goldspice on August 5, 2023 at 2:16 pm

    Hi all,

    I am awaiting an initial meeting with a cosmetic manufacturer who I’m sure will answer this but I wondered if anyone on here can shed some light in the interim.

    Is there any reason a product can’t contain 10% azelaic acid and 10-20% urea? What if the product also had 10% lactic acid? The type of product would probably be something you’d apply 2-3 times a week as an intensive treatment.

    Basically - is there any way to make the above work with the right additional ingredients? Any glaring issues with pH’s, solubilities etc that would make it impossible to create?

    I’m not a chemist myself, but curious to know if it is possible to achieve prior to my meeting with the company.

    Thanks

    Goldspice replied 1 year, 4 months ago 2 Members · 2 Replies
  • 2 Replies
  • Perry44

    Administrator
    August 7, 2023 at 8:22 am

    Mostly, that is just too much acid to be putting on a person’s face! Skin irritation could be a big issue. Also, Lactic acid works best below a pH of 4.0 whereas Azelaic acid works best at a pH of 4.9. So, adjusting the pH to a mid-point would just make both ingredients less effective.

    I wouldn’t recommend doing this.

    • Goldspice

      Member
      August 8, 2023 at 7:23 am

      Thanks Perry 🙂 I was hoping for it to be a body product but it seems too much even for that. I’ll re-evaluate things, thank you

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