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Anhydrous Cream Base
Hi Everyone,
I am trying to produce an anhydrous cream base for a bleach cream with hydroquinone. Any idea on how to make an anhydrous cream base?
Thank!
Geneva
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3 Replies
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There are a couple issues to address in this case. Some may be superfluous as I am unsure of your facility or background.
Firstly, Hydroquinone creams are OTC products and as such require Drug Facts labeling and an OTC Labeller. They are not and never should be something one would try outside of these regulatory controls.
Secondly hydroquinone is soluble in water and or Peg’s primarily. It is not soluble or very poorly soluble in lipids. AN anhydrous base would not work.
Here is a great article (excerpt only, requires registration for the full article) that you may fing helpful.
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I thought that in the USA hydroquinones are NOT over the counter products?
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No. They are covered under the OTC monograph. Hydroquinone 2% creams are sold OTC. Higher levels are prescription.
“All of the over the counter “bleaching” products that contain hydroquinone are limited to a 2.0% concentration in the United States. Prescription creams are usually 4% and dermatologists will sometimes specially compound ones that are higher strength.”
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