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What airtight containers do you use for stability testing?
Dear all,
I am looking for suitable airtight containers that are protected from light for stability testing. May I ask if you could share recommendations of what you use in your labs for stability testing please? Would greatly appreciate to see photos so I have an idea of what to look for. Thank you so much!
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9 Replies
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Stability should be conducted in your product package.
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thank you so much for the reply! ok, noted and will ensure to do so.
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I agree with @PhilGeis Stability testing should be done in the final packaging. If you are not using air tight packages with your consumer, the test would be almost meaningless.
We used simple 4 or 8 ounce glass jars with twist on caps. They weren’t “air tight” but they were good enough for stability testing. However, we also ran every formula in the package that they were going to be sold in. These were the samples that we used when deciding whether the product was stable or not.
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Thank you so much! Just to clarify further, would this mean that I should then prepare more cream sample in the actual product packaging versus glass jars so that I have enough to do the various testing on it over time? Would you also do freeze-thaw stability testing on samples in the actual product packaging please? Is it advisable to open and close the same glass jar to retrieve sample for testing every time? or would it be better to treat it as like an aliquot where once you’ve opened it, it is removed from the pool of samples and then for the next testing you take the next aliquot? Someone told me it would be more representative of how face creams are used in real life to open and close the same jar, but at the same time I want to make sure I am collecting my data carefully and properly. Hopefully my question makes sense…I come from a molecular biology background originally, but have now ventured into personal care formulations and am doing my best to learn all this from scratch. Sorry for the newbie questions…I am sincerely grateful for all the guidance.
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Yes. We always made batches to put stability samples up in both glass and the final packaging. It may have been over-kill but it’s generally helpful to know whether a formula is stable without interference from the packaging.
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Thanks so much Perry! Appreciate the guidance a lot.
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We order a glass jar from SKS. As Perry said this is more for product stability. Once the client obtains packaging, we then run compatability.
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Thank you so much! And also for sharing the photo, which is very helpful! We have similar jars in the lab, and I am glad to know that these can be used. That will help to cut down waiting time for delivery for me.
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The aforementioned samples were utilized in the determination of the product’s stability.
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