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NIACINAMIDE
HI
I formulated an o/w cream, and I did the stability tests, and it is stable, and I wanted from the same formula to reduce 4% of the water and to put niacinamide instead, so there the cream certainly has a very good texture but testing it with centrifugation at 3500 rpm for 30 min then there is a separation. can someone guide me? I tried two formulation methods 1: dilute niacinamide in the water of the aqueous phase and emulsify by controlling the temperature (not exceeding 75°C) and the 2nd: add niacinamide to the cold phase but always separation of the emulsion. what is wrong here?
????i used stearic acid 2%
emulagde 1000 ni 4 % CUTINA GMS 2% USING high shear 30 till 65°C then low shear till 45°C checking ph 5.6
any advices????
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3 Replies
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Hi,
Could you provide any more details? (at least full inci, final pH). How does the separation look?
Also, have you already done a knock-out experiment? Is the ‘base’ stable without NA?
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When you say that your original formula passed the stability tests, what tests did you do and for how long? Centrifugue aloneis not such a hard condition (many unstable emulsions can pass the centrifugue and the separate during the accelerated stability).
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When you say that your original method passed the stability tests, what tests were done and for how long? slope game
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