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Dilution Calculations for Hydrogen Peroxide 20 Vol
Dear Members,
I have hydrogen peroxide with Assay 400.4 g/kg. I need to dilute this to produce Hydrogen Peroxide 20 Vol.
My calculations are as follows.
Raw material concentration is 400.4 grams per 1 kg
= 400.4 grams per 869.565 mL (RM density is 1.15 g/L at 20 C)400.4 grams per 869.565 mL = 46.04 % w/v.
Hydrogen Peroxide 20 Vol. = Hydrogen Peroxide 6.071 % w/v
C1 x V1 = C2 x V2
46.04 x V1 = 6.071 x 1000 Lit
V1 = 6071/46.04 = 131.863 Lit = (131.863 x 1.15 = 151.642 kg)
For producing 1000 Lit of Hydrogen Peroxide 20 Vol, we need 131.863 Lit (151.642 kg) of Hydrogen Peroxide of 46.04 w/v strength.
Are these calculations correct ?
Please let me know at the earliest.
kind regards
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7 Replies
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Concentration x volume = concentration X volume
What do you mean by “20 vol.”?
Lose the excessive precision. -
Please check this product. I intend to make a similar product.
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20 Volume peroxide is 6.0% w/w since the SpG is close enough to 1.000, and standard concentration of commercial H2O2 FCC grade is 35.0% w/w. Just do the math.
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Can we use HDPE bottles for packaging of this Hydrogen Peroxide 6% w/w ? I have observed that the filled plastic bottles inflate after a few hours.
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@MurtazaHakim You can. The inflation you see is probably the hydrogen peroxide decomposing (the more you dilute it, the more chances it’ll decompose, especially under heat or in contact with copper and iron ions that might be present in your solution). To prevent that, you need low pH (below 5), the use of a chelant (HEDP is commonly used) and an antioxidant (like tBHQ).
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This inflation should not take place if I use RO water or DI water for dilution. The product https://www.medicines.org.uk/emc/product/4869/smpc#FORM has no such chelating agents indicated in the list of excipients.
Could there be another reason(s) for this inflation ?
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@MurtazaHakim If you read the list of excipients, they use Phosphoric acid, which means they protect the product by lowering the pH (probably below 5). Are you doing the same?
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