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Solubility of caprylhydroxamic acid in phenoxyethanol or glycerin
This preservative Phenostat composition is
Phenoxyethanol 70%
Caprylhydroxamic acid 15%
methylpropanediol 8%
Water 7%My question are
1. Is this methylpropanediol and water necessary to solubilize caprylhydroxamic acid in phenoxyethanol?
2. How much caprylhydroxamic acid can be solubilized in phenoxyethanol and be stored for later use?
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4 Replies
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Don’t know the answer to your question…but just gonna toss this out there. Someone in the know…. once whispered in my ear, that said acid is very incompatible with zinc.
Just a heads up when formulating with it.
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Graillotion said:Don’t know the answer to your question…but just gonna toss this out there. Someone in the know…. once whispered in my ear, that said acid is very incompatible with zinc.Just a heads up when formulating with it.
Thanks ????
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This mix may clash with this (rather annoying) Inolex patent. Because of the use of CHA and methylpropanediol in percentages covered in Claim 1.
“1. A preservative composition blend comprising about 4.5% to about 15% caprylohydroxamic acid or a salt thereof, wherein caprylohydroxamic acid is the only hydroxamic acid in the composition blend, and about 7% to about 95.5% of a diol selected from the group consisting of a propanediol, methylpropanediol, a butylene glycol, 1,2-pentanediol, 1,2-hexanediol, caprylyl glycol, 1,2-decanediol, caprylyl glyceryl ether, ethylhexylglycerin, glyceryl monolaurate, glyceryl monocaprate, glyceryl monocaprylate, and combinations thereof.”
https://patents.google.com/patent/US10897899B2/en
patents.google.com
US10897899B2 - Preservatives for cosmetic, toiletry and pharmaceutical compositions - Google Patents
A composition for and methods of preserving a topical cosmetic, toiletry or pharmaceutical formulation against microbiological contamination or growth are described in which the compositions used herein include at least one hydroxamic acid, salt or complex thereof, and the methods … Continue reading
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There’s also this patent, which is even more broad than the one I shared before.
US/8993641/B2
It looks to me that any use of CHA with diol in the US without using Inolex’ product is blocked but I am hoping I’m wrong.
Did you find a clever way to go around this?
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