Home Cosmetic Science Talk Formulating Dipropylene Glycol and Propylene glycol - natural origin

  • Dipropylene Glycol and Propylene glycol - natural origin

    Posted by IsaMa on December 16, 2021 at 12:06 pm

    Hi, I am looking for Dipropylene Glycol and Propylene glycol, but not from petrochemical origen. Do you know if it is available from a renewable source, either botanical or biotechnological? So far I could not find this alternative for those one.  Thanks!  

    Pharma replied 2 years, 11 months ago 3 Members · 2 Replies
  • 2 Replies
  • Microformulation

    Member
    December 16, 2021 at 6:05 pm

    Zemea (Propanediol) is plant-based and often used in place of PG.

  • Pharma

    Member
    December 16, 2021 at 8:33 pm
    You’ll have a hard time finding dipropylene glycol because it’s an ether and ethers are quite rare in nature.
    Propylene glycol can be prepared (synthetically using green chemistry) from renewable feedstock such as lactic acid but to my knowledge isn’t (yet) done on a commercial scale probably because production of propanediol (above mentioned Zemea) is more economical and ‘chemistry-free’.

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