Home › Cosmetic Science Talk › Formulating › Alpha Arbutin serum
Tagged: formula, formulating, preservatives, stability
-
Alpha Arbutin serum
Posted by Waleed636 on August 14, 2020 at 1:45 pmAlpha arbutin 2%
Hyaluronic acid 1%
Propanediol 2%
Glycerin 1%
Caprylyl glycol 0.4%
Ethyhexylglycerin 0.2%
Phenoxyethanol 0.4%
Polysorbate 20 1%
Chlorophenisen 0.1%
Dmdm Hydantoin 0.2%
Water to make 100%Open for suggestions
1501 replied 4 years, 3 months ago 6 Members · 10 Replies -
10 Replies
-
Maybe a little bit overkill of preservatives (better that way than the other way round).Why polysorbate 20%? Not saying it’s unnecessary, just asking for its purpose.
-
Pharma to make Caprylyl and ethyhexylglycerin dissolve and make serum clear
-
I wouldn’t use a PEG emulsifier to dissolve preservatives; too high a risk that they actually become inactive. The solubility limits are 0.3% for caprylyl glycol and 0.1% for EHG, smaller amounts of ‘solvents’ should hence suffice, you might even be okay with simply reducing their concentration or try the proposition of @ngarayeva001 . The only real bug food in your serum is HA, else, there is nothing inside which would necessitate such heavy preservation.
-
I have tried without Polysorbate but serum turns out to be milky and not clear the only purpose of polysorbate is to make serum clear
-
Is it the preservatives which cause the milky appearance? If so, upping pentanediol and/or glycerol to solve the issue would be a wiser strategy (from a theoretical point of view, not a consumer’s perception).
-
What preservatives did you guys used for Serum(gels) to have a clear solution?
-
Pharma said:Is it the preservatives which cause the milky appearance? If so, upping pentanediol and/or glycerol to solve the issue would be a wiser strategy (from a theoretical point of view, not a consumer’s perception).
Yes the ethyhexylglycerin and caprylyl glycol makes it milky
-
With 2% arpha-arbutin, the serum can be discolored by several months, I think so.
Log in to reply.