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Amount of bee venom in anti-wrinkle facial cream
What would be best / suggested amount of bee venom in anti wrinkle cream? In locally sold product I have found 0,01%. Someone recomended 1%. That is about 100 times more.
What would be your suggestion? -
13 Replies
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Since it doesn’t actually have any effect, 0.01% is the way to go.
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I plan to collect venom myself, so cost is not a big issue. However I would like to have effective, but safe product.
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What research has convinced you that topically applying bee venom will have any effect as an anti-wrinkle ingredient on skin?
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There exist medical studies that confirm efficiency of bee venom. From personal experience I can atest that bee venom helps for RSI.
But to go back on track, I would apreciate any guidance on dosage.
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According to this study, you would use 0.006%. Of course, the study is not a high quality one because they didn’t test against a standard moisturizer. Any moisturizer would give better results than the results from this study.
If personal experience is your guide then you use a high enough amount that convinces you it’s working. Only you can determine that.
Based on the research I’ve seen, I remain skeptical that it is a worthwhile ingredient to use for an antiwrinkle effect.
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My guide is to produce effective, but safe product. I acknowledge your skepsa regarding bee venom, however I would appreciate guidance regarding amount of used bee venom for facial cream.
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I honestly don’t know what you are looking for.
0.006% was tested in the study I referenced. So, if you want the results that they got in that study, use that amount.
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My question is regarding a different aspect. 0.006% is a very small amount. Any product must be consistent in the levels of the actives, even more so here with the small dose as well as the fact that it is being somewhat treated under the paradigm of being a therapeutic agent. If you are harvesting the venom yourself, what assets do you have to confirm the consistency of the product? This is going to require much more than just weighing the active, but also identifying the active and confirming the levels with analytical equipment.
Biological systems (bees included) can vary in the amount of active constituent in any harvested product. Products must be consistent within a defined range for active ingredients. How will you accomplish this?
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“Biological systems (bees included) can vary in the amount of active constituent in any harvested product. Products must be consistent within a defined range for active ingredients. How will you accomplish this?”
Great point!
How are you going to standardize the bee venom?
If you can’t find specific studies (not only that prove its efficiency, but also mentions the percentage range), you will have to make your own studies. What Perry found is a good start. 0.006% seems to confirm more the 0.01% you said in your first post. -
0,006% does seems a bit low. Even facial cream with 0,01% seems to low for me. On the other hand 1% may not be safe.
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I should think you’d get a real buzz off 1%
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I also imagine that if you were able to deliver any real concentration of active, you might find allergenicity progressing to anaphylaxis being far more significant than usual as well.
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@crazybean - You have to decide what kind of formulator you are going to be.
Are your formulation decisions based on science or are they based on your gut feelings?
The only evidence I could find related to the effectiveness of bee venom was a study that looked at 0.006% treatment. There is no scientific evidence to support putting in a higher level.
From a safety standpoint there is no good reason to use more of an ingredient than has been proven effective. There are good reasons to avoid using too much because there are frequent adverse reactions by consumers. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440710/
@belassi - lol!
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