Home Cosmetic Science Talk Formulating Trehalose solubility

  • Trehalose solubility

    Posted by belassi on May 19, 2016 at 8:08 pm

    Following on from the conversation about the ethanol-based body mister, I received the trehalose this morning and tried to incorporate it at a rate of 2% into a solution that contains 50% pure ethanol, 49% water and 1% fragrance.
    I am having issues with solubility.
    This link says that trehalose is soluble in water, but “slightly soluble” in ethanol. My problem is that I need to know its solubility more precisely than that.
    I found this result but I can’t understand the damn graphs! What is “Xa” and what is “X1” ??? Can anyone help? 

    Basically what I want to know is what is the maximum percentage of alcohol that I can use with a 2% solution. 

    David replied 8 years, 11 months ago 4 Members · 6 Replies
  • 6 Replies
  • belassi

    Member
    May 19, 2016 at 8:30 pm
  • belassi

    Member
    May 19, 2016 at 8:36 pm

    See example (6) for pet applications. Interesting.

  • Bill_Toge

    Professional Chemist / Formulator
    May 20, 2016 at 7:00 am

    about that graph, x1 is the mole fraction of water in a water/alcohol mixture, and xA is the mole fraction of trehalose dissolved in that mixture

    the graph shows that trehalose becomes completely insoluble when the mole fraction of water is about 0.04-0.05, i.e. about 2% water/98% ethanol, which is probably not helpful!

  • DragoN

    Member
    May 20, 2016 at 10:08 am

    Glad you liked that idea Belassi. May want to throw in some Cu gluconate as well..,useful. Makes for a lovely, refreshing light blue 

  • belassi

    Member
    May 20, 2016 at 2:21 pm

    It’s a great idea. I have no idea yet if it will sell, however.

  • David

    Professional Chemist / Formulator
    May 20, 2016 at 4:32 pm

    The graph is alright except it doesn’t show the interval of interest associated with the problem. We need to know what xA is when X1 is higher than 0,4

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