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Certainly! The pH of a solution can significantly affect the stability and activity of its components, including active ingredients like salicylic acid. Salicylic acid is most stable and effective at an acidic pH, typically around 3-4 https://labmuffin.com/fact-check-friday-why-does-ph-matter-for-ahas-and-bhas/ block blast. This is because salicylic acid has a pKa of approximately 2.97, meaning it prefers to stay in its non-ionized form at this pH, which is crucial for its ability to penetrate the skin and exert its effects.