[jessah]

ketchito said:

Hi @jessah. It’d be better to know specifically what type of issue you have that impairs your shelf life. There are few things that can provoke that like flocculation, pH drift, phase separation, color change, viscosity loss, odor change, etc. So, to better tackle your issue, perhaps you can describe your problem betteR

Hi! the main issue is the color change, because after 1 month in RT the color changes quick and I cannot change or remove one of the API because its what the Doctor’s need. Yes, smell is not pleasant then we add lavender oil for it. So yea, hoping to find a solution to make it more stable

[jessah]

ozgirl said:

Is the pH changing over time? It could be due to the urea.

hi! ph is within the range.. Urea we used 10%, so if we decreased the concentration there might be a chance to make it more stable?

[jessah]

Belassi said:

Isn’t hydroquinone banned?

Hi Sir! here in dubai its not banned.. and we are just compunding it as per Doctor’s prescription

[jessah]

ketchito said:

@jessah What’s the issue you’re experiencing with your formula? Maybe the problem is not the antioxidant. 

Hi! the issue is the shelf life.. as per our stability its only for 1 month.. and our goal is to make it stable for 6 months

[jessah]

We’ve tried 5 trials for salicylic acid 40% gel, but still none of them worked.. For lotion i dont have any formulas found online thats why i cannot start with it. 

[jessah]

Fekher said:

@jessah  you must use 40% salicylic aid in gel form? 

Salicylic acid 40% Gel or lotion.. If i have both formulas, its so much better

[jessah]

chemicalmatt said:

jessah: STOP there at 30% salicylic aid. That’s my advice. You have wart remover there, not a skin-care product.

Hi! apparently i am working in a compounding pharmacy, and we are compounding upon the Doctor’s prescription/requests. So this 40% its the Doctor’s request from us either gel/lotion but then ive searched online and it seems i have no luck in finding formulation for 40%. 

[jessah]

i tried with IPA but the same result