[Dynamin]

SauerLaura said:

Dynamin said:

Actually, my solution has to penetrate into the papilla of the hair follicle

What for? As far as I know, follicles feed on blood from the inside, and not something from the outside. Ingredients long fall into the dermis. In addition, the issue of convenience: propylene glycol, for example, gives oily scalp.

Laura, the product I’m working on is a minoxidil supplement, and only needs to go down to the dermis as far as the papilla resides

[Dynamin]

Bill_Toge said:

Microformulation said:

DMSO is not generally used in Cosmetics. It is also not as innocuous as many believe.

and that’s why it’s been banned in European cosmetics since 1979

If it has been banned, there sure are a lot of UK outlets selling it:

https://www.google.ca/search?q=dmso+site:.co.uk&lr=&source=lnms&tbm=isch&sa=X&ved=0ahUKEwiwvbeNncbgAhXDyoMKHXM2BAUQ_AUIDigB&biw=1280&bih=551

And this was before BREXIT of course

[Dynamin]

Sibech said:

@Dynamin What would they have been sued for? You cannot sue a properly labelled solvent, which the end-user abused, can you? (I don’t know, I am not an attorney nor am I based in the US).

If I’m injured by someones product, it doesnt matter how many warning labels they put on it, they can still be held liable.  Especially if the injuries are serious enough

[Dynamin]

Sibech said:

 @dynamin Notice how they all write: Intended for use as a solvent only (or something to that effect), that is likely there in the hope it will keep them out of legal issues when using DMSO.

While standing with what I previously wrote, another option for a penetration enhancer Tetrahydropiperine, which will likely increase the bioavailability of your vitamins.

Fair warning, keep an eye out for regulations. As @m@Microformulation mentioned you get close to a Drug in the US. You may also Borderline Drug/Medical Device in the EU.

Fair point Sibech, but if people had gotten sick from their DMSO products they wouldve been sued into oblivion by now already

[Dynamin]

ngarayeva001 said:

The Ordinary use DMI in many of their products. But in many cases you don’t really need the product to penetrate deep. It really depends on your actives and the formula in general. “Propylene glycol doesnt work, its not strong enough” is a blanket statement.

Actually, my solution has to penetrate into the papilla of the hair follicle

[Dynamin]

DMSO is widely used as a penetration agent in lots of creams that contain other substances (eg. Aloe Vera, Hyaluronic acid, Vitamin E, B17……..etc…….etc).

See here: https://www.google.ca/search?q=dmso+cream&lr=&source=lnms&tbm=isch&sa=X&ved=0ahUKEwj8xuDE2sXgAhUC8IMKHZkpAK0Q_AUIDygC&biw=1280&bih=551