Home Cosmetic Science Talk Formulating Preservative lexguard HPO

  • Preservative lexguard HPO

    Posted by Nyatou on January 29, 2025 at 1:05 pm

    Hi,

    kindly asking for opinions regarding this preservative efficacy boosted with some EDTA, 2% glycols and pump containers. Composition is 45% caprylyl glycol, 30% phenoxyethanol and 10% hexylene glycol.

    It is said to be effective in water only products at 1%, an addition of 0,3% of glyceryl caprylate is highly recommended in lotions.

    Thanks in advance

    PhilGeis replied 22 minutes ago 2 Members · 4 Replies
  • 4 Replies
  • PhilGeis

    Member
    January 29, 2025 at 2:10 pm

    Glycols and phenoxy are weak vs fungi.

    Highly recommended? Maybe the supplier but doubt anyone familiar with preservation would recommend glycerol caprylate

    • Nyatou

      Member
      January 29, 2025 at 4:58 pm

      I appreciate your expert input. I will add some sodium benzoate. Whenever I add some sodium benzoate I do calculations doing the Henderson–Hasselbalch equation. I have read in this group before that in order for sodium benzoate to be effective there must be 0,1% in protonated form. Is that correct? Based on my calculations 0,25% is the needed amount at pH 4.5.

      Thanks a lot!

  • PhilGeis

    Member
    January 30, 2025 at 5:17 am

    I understand and don’t find that so useful. We’re working in dynamics of formulas, microbes and consumer use. There is some degree of consistency/predictability and it more Edisonian than formulaic - derives from efficacy in formulas in use. Most folks here don’t have the luxury of on-demand validated challenge testing and post consumer use survey so they’re best advised to reapply the basic stuff within identified safe in use ranges.

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