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PAO’s
How are PAO’s established for completed formulas ? What calculation methods are used to determine the PAO timeline?
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3 Replies
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Typically, you would do stability testing to set a PAO.
In reality, there is no established method and companies are left to come up with their own methods. It is a bit of a ruse because if you don’t know when the consumer first opens the product, you couldn’t realistically set a PAO. For example, if the consumer opens the product 1 day after they purchased it, that will last a different amount of time than if a consumer opened a product 1 year after they purchased it.
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So if a formula passed a 3 week stability and then a 3 month study, what could be safely established ? Anhydrous formula containing a natural preservative system and sales. Basically a scrub for the scalp .
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