Home Cosmetic Science Talk Formulating Niacinamide PC and Vitamin C

  • Niacinamide PC and Vitamin C

    Posted by Lindsay on December 9, 2015 at 8:22 am

    Does anyone know of a reason why not to combine Niacinamide PC with one of the Vitamin C derivatives ( Ascorbyl Tetraisopalmitate) in the same product?  The final pH of the formulation is close to 5.5.  Are they compatible?

    sandydijon replied 9 years, 4 months ago 2 Members · 1 Reply
  • 1 Reply
  • sandydijon

    Member
    December 12, 2015 at 10:29 pm

    I tried not to mix Niacinamide into any acidic formula because this is what I read about Niacinamide.

    Niacinamide: Typical concentration is 1-6 %, with 5% being a typical and effective
    concentration. For external use only. Avoid adding to an acidic product,
    ideal final pH of product should be 6. Should not be combined with
    l-asorbic acid. It can hydrolyze and form nicotinic acid at higher or
    lower pH, which can result in skin irritation.

    But I have seen a lot of vitamin C hyaluronic serums sold on Amazon contain Niacinamide and Vitamin C and no pH adjustor. Do you think we got a lot of “unsafe” products out there?

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