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Looking for someone who can formulate 4% Hydroquinone cream
Please guys I need help, I am looking for someone who can take up my project, most of the Labs that I have contacted did not work with hydroquinone and its frustrating me.
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13 Replies
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Well, there’s very good reasons for that.
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Have you checked the regulations on creams containing hydroquinone in creams containing more than 2% HQ? … Where are you located/intending to market?
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Belassi I know, it’s so difficult to find someone. I actually need 2% of hydroquinone because that is there recommendation rules.
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HI Mark, I have check the regulations but I wanted 2% of hydroquinone on my formula.
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I can only speak to US standards, but in the US up to 2% Hydroquinone is an OTC. Above 2% is a prescription product.
I am familiar with the Formulating, but to be honest it has been years since I have been seriously approached. In our area, Cosmetics, there is a strong Market bias due to safety concerns. I see a great deal more requests for Arbutin, Kojic acid and numerous other botanical based tyrosine inhibitors.
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Hydroquinone is banned in the EU at any concentration in cosmetics. Unless you are operating in a jurisdiction where it is allowed, I’d look for other skin lightening alternatives.
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Mark, can Arbutin and kojic acid work better to lightening the skin too? What other lightening agents will be effective.
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If you are going to make an effective product, you will need to refine who your target client is.
When we covered this in school, the starting point was to discuss the Fitzpatrick Scale. This an objective scale Dermatologists use to gauge skin pigmentation; https://en.wikipedia.org/wiki/Fitzpatrick_scale
Generally (these are generalizations), Type VI is Western African or similar dark coloring. These clients respond better to Kojic acid and more stable derivatives. Kojic acid is unstable and generally the Dipalmitate salt is used.
Type V and IV is generally Pacific rim and Indian continent. In my experience these clients respond best to Arbutin.
In all these groups you will see naturally sourced botanicals added for additional or (arguably) primary effect. Bearberry and Licorice extracts are common. Licorice and some of the newer derivatives show some great promise.
Now, all this assumes you are looking for bleaching. If you are looking to treat age related discoloration, there are other modalities.
I would suggest reading a credible general overview of these treatments before continuing. Once you decide upon an active ingredient, there is a great deal of information from the distributors. Also, read the Technical data sheets from the distributors. Each active does have some specific factors to consider in the Formulation.
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Microformulation thank you for the information, my target clients are African. I will take on board this.
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Just FYI there are a couple sample formulas on UL that you can look at to give you a path to follow.
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@Microformulation - Thanks for the link. I didn’t know that forum archive was still available.
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Thank you @Microformulation
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