Pharma
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Comments
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Check out Ajinomoto, they are the ones who invented these surfactants (or at least managed to produce it large scale).
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They can get cloudy at lower temps . Bring them to 25-30°C and if they become clear again, they're okay. Polysorbates are very stable: Tween 60 is visually stable for years but might get cloudy at higher temps when getting old whilst polysorbate 80…
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Wouldn't it be fairly easy to reverse engineer a cream simply by using chromatography (HPTLC/HPLC/GC) and mass spectroscopy? Depending on composition (cause polymers and extracts are not so easy going) and given that you have concentration curves of…
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Abbass_1 said: My Question is: just like we have pH control for preservatives and anionic/cationic surfactants, do we have the same for TDS? I still don't really get it. TDS is everything dissolved in water which doesn't evaporate upon…
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Meemcha said: ...May I trouble you for a brief explanation of that 3:1 limit as recommended concentration of Polysorbate 20 is usually up to 10%. What am I missing here? That's just a rule of thumbs. In order to be transparent or at leas…
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Use distilled or demineralised water .
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Perry said: ... Micellar water is a marketing term, not a scientific term. You can call whatever you want micellar water. The only question is whether your consumers believe it. Not quite; sure, micellar water is mostly used as marke…
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teyodora said: Opinions on Methylchloroisothiazolinone in rinse off products? It's omnipresent in many household chemicals such as dish-washing liquids, floor cleaners, room sprays, or paint. Like many chemicals with such widespread use,…
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No TEA. REAL cold cream does neither contain an emulsifier nor emulsifying wax. Some add it or use small quantities of sodium lauryl- or laurethsulfate to help the emulsifying process and increase emulsion stability but the trick of cold creams is t…
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My favourite base formula for cold creams is the one from Dermatologische Magistralrezepturen der Schweiz: Beeswax 8 Hydrated peanut oil 17 Refined peanut oil ~50 Castor oil 5 Water …
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ORAC is just on of many antioxidant tests done. Each has advantages and peculiarities and may be extrapolated to some conditions but not to others. There is not THE strongest antioxidants, there's just some which are under certain conditions better…
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@Dr Catherine Pratt? Guess I miss something here (lost in translation or overworked?), sorry ;( . Petroleum jelly is safe. Legend has it that the guy who "invented" Vaseline (IIRC he, I unfortunately forgot his name/company, didn't but was owner of…
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Best is to ask your client for a list of preservatives they define as 'natural'. Some of the 'bad chemicals' also exist in nature whereas 'natural' ones don't exist in nature. Also, several of both classes are produced in a similar fashion just that…
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Cst4Ms4Tmps4 said: ... I have been wondering how come Glycerin is seemingly the only thing that gets absorbed that efficiently, it is not even cationic... ...Can Sorbitol penetrate aquaporin and be resorbed like Glycerol? Sorbitol is twice the…
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That's what I've learned too. Silicones 'breath', so to say. What's your difference between mineral oil and petrolatum?
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Zabi said: Yes mercury is banned but tell me the process of using. You won't get a recommendation because mercury is banned in most countries for most uses. There are exceptions but you're not part of those or you wouldn't ask said quest…
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Hirondelle21 said: ...zap in the microwave for 30s...great for travel. 'merica, where people have a built-in microwave in their car! ...100% natural is a tall order and also that natural is a pretty loose term... A good part of the ingredien…
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IPA dries faster and comes, at an affordable price, water-free whilst ethanol is usually no more than 96% or, if anhydrous, is fairly expensive. Solubility properties aren't better or worse, they are simply different. Higher hydrophilicity and pola…
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Could also be Cosmospheres (i.e. microcrystalline cellulose plus lactose or mannitol) .
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raiyana said: ... "are you pregnant? are you breastfeeding?".... Unfortunately, that's about common practice ;( . I think that at least in Europe and USA, two negative pregnancy tests before the first prescription and double-contraceptio…
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pccochran said: ...Why would taurine have that kind of preservative effect? ... It is likely the coincidental result of ionic strength, ion type, buffer capacity, and probably pH which has an impact on Debye length, Zeta potential, and …
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Fortunately, skin penetration is piss poor for tretinoids! But they all rely on living cells because their effect is mediated via gene expression. Faster shedding is due to faster cell differentiation/maturation = (hypothetically) faster cell life =…
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EVchem said: ...Have you ever prepared any emulsions with this? Yes, during my PhD. More precisely a micellar solution, see THIS publication, section 'Measurement of IL-1β maturation and secretion'. Very easy to prepare since it's self-…
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@EVchem ascorbyl palmitate, not phosphate . 't was a typo by @MarkBroussard.
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ngarayeva001 said: Beeswax is not an emulsifier... ...Oils don't do anything good for hair except for making it greasy and heavy. Oils are added at 0.5% maximum for claims only. Bottom line: hair needs cationics and silicones, not oils and but…
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Dang, I can't find the information we've got anymore, it was from this summer about latest data regarding birth defects. Official sites and up-to-date go-to pages such as embryotox.de still have retinoids listed as no pregnancy for 1 month post ther…
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You could make sodium or potassium salt from it and that use as anionic emulsifier which spontaneously forms micelles above ~35-40°C.
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Yea, brightening complex, that's what my shrink diagnosed! Told me that I'm having a brightening complex cause I'm under the illusion of being brighter than everyone else . Tretinoin is a prescription drug here around. It sure does a great job but…
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A spoon? Now that right there might be the answer to your issue . Use the blender in the beginning and stir at low sheer (manually if you want to) until cooled down. Sour smell? Not that I know how it smells but I imagine it shouldn't be sour. As…
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Isn't THIS the 'facts sheet' and THAT the therein cited publication? Weird that they name it saccharide isomerate since, by definition, it's not a saacharide isomerate but a modified exopolysaccharide... Also, it's strange that the publication whic…
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