Home Cosmetic Science Talk Formulating What solvent can be used to dissolve silymarin that is also safe for human use?

  • Graillotion

    Member
    February 10, 2025 at 10:39 pm

    How about ethanol? That is so safe…I’ve actually even heard of people drinking it. 🤣

  • Herbnerd

    Member
    February 11, 2025 at 10:00 am

    Silymarin is soluble in ethanol; and also in acetone - most commercial extracts use 95% ethanol or acetone for extraction purposes.

    Ethanol is used if it is intended to be extracted for consumption as a tincture or fluid extract. I have also seen glycetracts where the silymarin is extracted using glycerin; however, most commercial silymarin extracts sold as concentrated powdered extracts standardised to silymarin use acetone and dried.

    If you are extracting yourself, a simple tincture of 1000 ml of95% ethanol, and 200 g of silybum marianum seeds - ground and extracted over a couple of weeks will give you a 1:5 tincture. If you wanted to go to 1:2 fluid extract, the extraction is done through percolation.

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