• Formulating

  How to prevent Tetrasodium EDTA from crystalization

  Posted by Abdullah on December 31, 2022 at 6:20 am

  I have a product with simple 0.3% EDTA + preservative in water pH 5.1. it is stable but now at temperature sometimes -10°c EDTA crystalizes.

  How to prevent EDTA from crystalization In cold weather like -10°c? 

  ketchito replied 1 year, 11 months ago 3 Members · 3 Replies

  • crystallization
  • edta
  • solution
• 3 Replies

• 

  Graillotion

  Member

  December 31, 2022 at 9:27 am

  I found the easiest way…was to use GLDA.   

• 

  Abdullah

  Member

  December 31, 2022 at 9:59 am

  Graillotion said:

  I found the easiest way…was to use GLDA.   

  It is not available locally unfortunately

• 

  ketchito

  Member

  December 31, 2022 at 12:06 pm

  @Abdullah Did you reduce the pH of your solution? Tetrasodium EDTA in water has a pH closer to 11. At a pH of 5.1, you have a different species which is less soluble in water. You could increase pH to prevent precipitation.

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