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Curoxyl 42 - Any tips on using it?
Hello All,
I was wondering if anyone has had success with this material? I’ve tried using it at the manufacturers guidelines with no success, especially at room temp. I got this material so it would be easier to use but it’s proving the opposite.% DI Water 90.10 Sepigel 305 3.00 Curoxyl 42 2.50 Glycerin 1.00 Euxyl PE 9010 0.90 Extract in water/BG 2.50 I’ve also tried a similar formulation with Sepimax EMT 10/ Sepimax Zen.
Any tips or advice are welcome! Thank you. -
17 Replies
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Write the INCi names
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@KimberlyLars better make sure everything there is peroxide stable or you will be sorry. Sepigel 305? Which “Extract”?
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@KimberlyLars As @chemicalmatt mentioned, you need to have materials resistant to peroxides, which not be the case with your current formula. If you want to make a gel, you can find some gelling agents that work well with oxidizing agents (like Carbopol 674 although, not sure if it’s approved for cosmetics). You could actually build a gel using surfactants.
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How will you address stability?
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Curoyl 42 is in a Carbomer base, if I recall. So, your best bet is to use Carbomer as your gelling agent, but double check on that.
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Curoxyl 42 has an INCI name of Water and Benzoyl Peroxide. There is a very good guiding document available for download here; https://www.ulprospector.com/en/na/PersonalCare/Detail/705/217985/Curoxyl-42?st=1Off-hand and from experience, you will likely need a better emulsification system.
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Sample Formulation. http://dir.gcimagazine.com/detail/formula.html?id=1348
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For those asking for INCI names:
Water90.10 Polyacrylamide
& C13-14 Isoparaffin & Laureth-72.00 Water (and)
Benzoyl Peroxide2.50 Polysorbate 20 1.50 Phenoxyethanol
(and) Ethylhexylglycerin0.90 Extract in
Butylene Glycol2.50 Hydroxyethyl
Acrylate/Sodium Acryloyldimethyl Taurate Copolymer0.50 -
@Microformulation thank you for the feedback. I found their formulation tips to be unhelpful as I did exactly as instructed with no success. Thank you for providing the sample formulation.
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PhilGeis said:How will you address stability?
Typical stability with light, dark, 25°C, 40°C, 4°C, Freeze/Thaw
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KimberlyLars said:@Microformulation thank you for the feedback. I found their formulation tips to be unhelpful as I did exactly as instructed with no success. Thank you for providing the sample formulation.
I have used the product numerous times and have had no difficulty getting a homogeneous product with an overhead stirrer. (IKA Eurostar Digital).
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KimberlyLars said:PhilGeis said:How will you address stability?
Typical stability with light, dark, 25°C, 40°C, 4°C, Freeze/Thaw
Curoxyl 42 as Benzoyl peroxide - I assume you’re including this as an anti-acne active. How do propose its determine its stability. Be aware - if you’re in US -this will be a drug product.
Also - don’t understand the apparent comparison tio Sepimax. -
@KimberlyLars It’d be good also to check for initial and final peroxide content, since peroxides tend to degrade in aqueous media (pH can also accelerate degradation).
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isn’t this explosive?
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Stanley said:isn’t this explosive?
No. Where did you get that?
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Stanley said:isn’t this explosive?In pure Raw form it is. But market available form are 40% (aproxi).
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And I also think good quantity PG & EDTA also help.
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