Hello everyone, thank you in advance for your time and help.
First of all, i’m not a professional Chemist, i’m Just a DIY kitchen maker, so please be patience with me.
However, i would like to increase the soothing power of my lotions by using this active substance, but unfortunatly i can get only the water insoluble form who, like the technical datasheet explain, is “Practically insoluble in water; soluble in ethanol, in ether, in pyridine and in acetic acid; very soluble in chloroform and dioxane”. I tried with the only solvent I can easily get and that it is not too harmful to the skin, ethanol, but the solubility is really low; in fact, I obtained a crystalline solution with an ethanol: GA ratio of 20: 1, and I don't want to put such a high percentage of alcohol in a cream for delicate and reddened skin. the technical data sheet suggests using this active at 2%, so decreasing the doses of solute to proportionally decrease the amount of solvent would seem useless.
I read with interest that Belassi synthesizes the dipotassium glycyrrhizinate starting from Glycyrrhetinic acid and making it react with KOH, but I guess it's something I can't do with my home "powerful tools" LOL.
So, if anyone could suggest some elegant and applicable solution to my problem, I would be genuinely grateful to test your valuable suggestions.
thanks again for your time,
Ps: sorry for my poor english, is not my mother tongue, i’m from Italy.
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