Why can't collagen and elastin be permanently injected?

That may sound like a stupid question but I don't understand why they can't be injected into the skin of aging people to reverse wrinkles and sagging for good. Or why not fat. Is there no way of inserting a form of collagen and elastin that won't degrade?

It'd be better than Botox or fillers. Even when you see celebs with that stuff, it doesn't make their faces doesn't look like they used to...even though that is the intention.

Comments

  • Collagen and elastin are macromolecule, it contain amino acid which can act as allergen, if you sure use human collagen or elastin its might be possible, but if it derivate from porcine or bovine are you want to inject that to your body?
  • PerryPerry Administrator, Professional Chemist
    I also think because it's a biomolecule that is naturally broken down over time. It's the same reason the collagen and elastin that your body produces doesn't last forever.
  • MarkBroussardMarkBroussard Member, Professional Chemist
    Yes, Collagen and Elastin break down over time and as you age you produce less of each.  I don't know of any injectible that does not naturally degrade once injected into the body.
    Chemist/Microbiologist formulating in the Organic & Naturals & Clean Beauty arena under ECOCert/Natural Products Assn/Whole Foods/National Organic Program/Clean At Sephora/Credo Clean guidelines focused skincare & haircare products. 

    See website for details www.desertinbloomcosmeticslab.com
  • PerryPerry Administrator, Professional Chemist
    @MarkBroussard - I suppose there are plastics you could inject that might not degrade in the body over time.

  • MarkBroussardMarkBroussard Member, Professional Chemist
    Yes, Perry ... you may be correct


    Chemist/Microbiologist formulating in the Organic & Naturals & Clean Beauty arena under ECOCert/Natural Products Assn/Whole Foods/National Organic Program/Clean At Sephora/Credo Clean guidelines focused skincare & haircare products. 

    See website for details www.desertinbloomcosmeticslab.com
  • MacrophageMacrophage Member
    edited October 2021
    Yes, Perry ... you may be correct


    spot on 
  • PharmaPharma Member, Pharmacist
    Collagen and elastin fibres need to be in a precise orientation in a specific place in order to work. It's not like the 'random gel' formed by hyaluronic acid. Sure, HA in theory has a very fast catabolism but somehow (I suppose due to its tremendous water binding) does degrade slower than pure proteins such as collagen and elastin. The latter would likely just form some sort of lump in the connective tissue without doing anything to the skin above.
  • Yes, Perry ... you may be correct


    🤣🤣🤣🤣
  • Yes, Perry ... you may be correct



    Please tell me that's photoshopped.
  • MarkBroussardMarkBroussard Member, Professional Chemist
    Nope ... that is not photoshopped ... it's two twins in the film business.  There are some actors/actresses who have grossly disfigured their faces with plastic surgery and injectibles.

    Sad thing is, when they look in the mirror, the probably think they look great.
    Chemist/Microbiologist formulating in the Organic & Naturals & Clean Beauty arena under ECOCert/Natural Products Assn/Whole Foods/National Organic Program/Clean At Sephora/Credo Clean guidelines focused skincare & haircare products. 

    See website for details www.desertinbloomcosmeticslab.com
  • Perry said:
    @MarkBroussard - I suppose there are plastics you could inject that might not degrade in the body over time.

    There is but not approved as filler so don't look for it @Perry, you look fantastic the way you are.
  • What about injection of brown adipose tissue?
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