I made gel for methyl ester in 40% ethanol using carbomer 940, ph 7.2
After 1 month the gel turn liquid.
No significant ph change observed.
What could be the reson and solution.
Also i tried to change the gelling agebt and used hpmc but i gives dryout layer.
Any suggestions for the carbomer.
And if i want to change the geeling agent, any suggestions