CIT/MIT AND DMDM-H COMBINATION


Sodium Peg-7 Olive Oil Carboxylate,
Liromid Mipa,
Olive Oil Peg-7 Esters,
Peg-40 Hydrogenated Castor Oil,
Olea Europaea Olive Oil,
Dmdm-Hydantoin, Methylchloroisothiazolinone, Methylisothiazolinone

Hello, why do you think DMDMH and CIT / MIT were used together in this formulation? 
While there are other alternatives with a wide pH range, the combination of limited use elsewhere (DMDM-H) and claimed to be dangerous (CIT / MIT) seemed strange to me and I could not understand why.

Thanks for your ideas...

ps: ıt is a liquid hand soap 

Comments

  • PerryPerry Administrator, Professional Chemist
    It's difficult to say for sure but it may have nothing to do with the formula and more to do with their production facilities.

    You see, sometimes a filling line can get contaminated with a "house bug" that forms a biofilm which is resistant to cleaning. Every batch you run through that filling line can potentially become contaminated with little spores that break off as product flows through.  CIT / MI is very good at immediately killing off these types of microbes.  So, some factories will just put CIT / MI in every formula because it is used at a tiny level, is effective, and rarely affects stability.

    Now you might be wondering if CIT / MI is so good at killing why don't they just clean their filling lines with it?  Well, that's because while it can kill of individual spores, it isn't able to kill off the whole biofilm.

    That's my guess anyway.
  • BelassiBelassi Member, PCF student
    How disgusting.
    Cosmetic Brand Creation. Concept to name to IMPI search to logo and brand registration. In-house graphic design inc. Pantone specs. Cosmetic label and box design & graphics.
  • PerryPerry Administrator, Professional Chemist
    The world of contract manufacturing isn't always pretty.
  • BelassiBelassi Member, PCF student
    I view it this way. I've worked in a bar and cleaning out the pipe systems is something that has to be done regularly and done 100% properly. For the same reasons, possibility of a biofilm. Now imagine if I had to tell the customers, "There is a possibility of a biofilm in the pipes so we put a preservative in the beer to kill any nasty bits that might break off and get in your beer."
    How long do you think the bar would stay in business?
    I don't regard it as remotely acceptable that any kind of biofilm is present in pipes that are processing a consumer product. Not at all, not in any circumstances.
    Cosmetic Brand Creation. Concept to name to IMPI search to logo and brand registration. In-house graphic design inc. Pantone specs. Cosmetic label and box design & graphics.
  • Hi @Perry ; I'm starting production in my own company. that's why I review many brands. As a result of my research, I found the Ethylhexylglycerin / Phenoxyethanol mixture suitable for my own prescriptions. 
    I plan to take the product from the mixer boiler to the waiting boiler with a vacuum hose and send it to the filling line.

    Do I need to take other precautions for products such as shower gel and liquid soap?

    I don't want to use protectors like CIT / MIT and DMDMH.
    Thank you...
  • @Belassi thanks for your comment...
  • Usually when I see multiple preservatives when not all would be necessary I assume that some fraction of the unnecessary ones are pulled in by the preservation requirements of individual raw materials. The INCI declaration of the raw materials may have their preservative listing required (that is insufficient to preserve the entire formula) and that may be different then the standard preservatives the contract manufacture typically uses. Usually its more identifiable by botanicals and surfactant blends. I don't see any stand out materials that would make it so in this case but figured I'd throw the idea out there to be considered.
  • @filiz My guess is that since some free amines that are present in amides (like your Liromid Mipa) can reduce the potency of Isothiazolinones, it's common to add a formaldehyde releaser like DMM hydantoin to hinder free amines. 
  • PerryPerry Administrator, Professional Chemist
    edited October 2020
    @RDchemist15 - Great point. That is also another reason you would see multiple preservatives listed.

    @Belassi - I completely agree with you. I hope I did not give the impression that I thought it was acceptable behavior. I was quite surprised when I learned that this type of thing went on at some facilities.


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