Alpha Arbutin serum

Alpha arbutin 2%
Hyaluronic acid 1%
Propanediol 2%
Glycerin 1%
Caprylyl glycol 0.4%
Ethyhexylglycerin 0.2%
Phenoxyethanol 0.4%
Polysorbate 20 1%
Chlorophenisen 0.1%
Dmdm Hydantoin 0.2%
Water to make 100%

Open for suggestions

Comments

  • PerryPerry Administrator, Professional Chemist
    Without a question, there isn't much advice to give.

  • PharmaPharma Member, Pharmacist
    Maybe a little bit overkill of preservatives (better that way than the other way round).
    Why polysorbate 20%? Not saying it's unnecessary, just asking for its purpose.
  • Pharma to make Caprylyl and ethyhexylglycerin dissolve and make serum clear
  • Propanediol might be sufficient for that
  • PharmaPharma Member, Pharmacist
    I wouldn't use a PEG emulsifier to dissolve preservatives; too high a risk that they actually become inactive. The solubility limits are 0.3% for caprylyl glycol and 0.1% for EHG, smaller amounts of 'solvents' should hence suffice, you might even be okay with simply reducing their concentration or try the proposition of @ngarayeva001 ;) . The only real bug food in your serum is HA, else, there is nothing inside which would necessitate such heavy preservation.
  • I have tried without Polysorbate but serum turns out to be milky and not clear the only purpose of polysorbate is to make serum clear
  • PharmaPharma Member, Pharmacist
    Is it the preservatives which cause the milky appearance? If so, upping pentanediol and/or glycerol to solve the issue would be a wiser strategy (from a theoretical point of view, not a consumer's perception).
  • What preservatives did you guys used for Serum(gels) to have a clear solution?


  • Pharma said:
    Is it the preservatives which cause the milky appearance? If so, upping pentanediol and/or glycerol to solve the issue would be a wiser strategy (from a theoretical point of view, not a consumer's perception).
    Yes the ethyhexylglycerin and caprylyl glycol makes it milky
  • 15011501 Member
    With 2% arpha-arbutin, the serum can be discolored by several months, I think so.
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