Efficient sanitizer for Coronavirus?

FekherFekher Member, Professional Chemist
edited March 22 in General
Hi experts, it is soo important to share your knowledge about coronavirus which is thread for us, all mankind so we must all help each other to win the war.
I see that for coronavirus sanitizer have 75%IPA or 80%ethanol so the lower level will not work for coronavirus???!! 
All share here about sanitizer talk about 60%and 70% alcohol's level which seems not efficient for coronavirus??
Hydrogen peroxide is it must be in Coronavirus Sanitizer? 
 Liquid soap based on LABSA or N70 is it effective solution for coronavirus??
Our duty all as professionals to share true knowledge and right solutions for others. 
@Perry @Chemist77 @Gunther @lmosca @ozgirl @Pharma @Bobzchemist @Cafe33
@ngarayeva001

Comments

  • PharmaPharma Member, Pharmacist
    Fekher said:
    ...
    I see that for coronavirus sanitizer have 75%IPA or 80%ethanol so the lower level will not work for coronavirus???!! 
    All share here about sanitizer talk about 60%and 70% alcohol's level which seems not efficient for coronavirus??
     Liquid soap based on LABSA or N70 is it effective solution for coronavirus??
    ...
    Higher % is simply more efficient against viruses such as SARS-CoV-2 than lower % which is fine against bacteria. Lower % is better than nothing but given the choice, go with the WHO recommendations.
    Soap is poorly understood and we still lack valid data which soap is more or less efficient. IIRC @Perry posted something in this regard. The main effect of soap is not to destroy viruses but to mechanically remove them. In everyday life, regularly washing your hands with soap (for at least 30 seconds) has proven a valuable tool to reduce bioload and infection risk.
    A: Stick to the recommendations given by WHO, CDC, ECDC etc.!
    B: If you're not sure what you do, don't do it!
    C: This is not a beauty topic but serious business which puts lives in danger if done wrong and therefore should be left to health professionals or at least those who stick to the rules given by health authorities!
    D: Only formulations approved by above mentioned organisations may be called antivirals or disinfectants without further testing. All other concoctions and formulations require proper antimicrobial testing, else they are just something like cosmetic refreshment products.
  • FekherFekher Member, Professional Chemist
    edited March 22
    @Pharma thanks for share what do you think about hydrogen peroxide?
    I Ask for that cause it not available for me and I want to make real effective coronavirus sanitizer, so I want to know really if formulation will work or not without it.
    I readed in link shared by @Perry that hydrogen peroxide is not active in formulation but it used for eliminate contamination.
    So I guess formulation will be effective without it. 
  • PharmaPharma Member, Pharmacist
    The WHO formulation only contains H2O2 because the sanitiser should also work against everything and be clean even if prepared under low hygienic standards. That's why they recommend traces of H2O2 to get the product as clean as possible. It has no use against the coronavirus and you can leave it be.
  • DASDAS Member
    First, there is a key factor that you need to understand. This is a new virus, therefore the information we have is limited. Governments and companies have to study the virus to know more, and that won't happen for at least a year. The big companies don't have access to the virus just like that, there are protocols to follow and that takes time. Meaning we don't know shit and we won't for a while, as simple as that.

    What we know is that there are similar viruses that have been studied, therefore we use what we know about them. That doesn't mean it will all work the same. Will this coronavirus be as resistant to ethanol? We don't know. Will this coronavirus give us contradictory results when tested against benzalkonium chloride? we don't know. Will following formulation guides for a similar virus be effective? WE DONT KNOW. But that's the best we got, so that's what we are doing. Mostly to avoid spreading fear amongst the consumers, imagine the panic if we say "we can't assure anything". 

    So we use what we know. What's that?. That this one's a fatty, meaning surfactants will work. Will it kill the virus? no in a short period of time, but it helps. So the important thing is to follow the good practices to mecanically remove it, wash your hands, don't touch your face, and most important don't be around people. Stay at home, that's the best we got, and what's 100% efficient and proven.

    The rest is psychological, you don't need hand sanitizer if you don't go out, but people need to have it. It's a placebo with an unknown level of efficacy. Good for us, sales spiked.
  • Cafe33Cafe33 Member
    Okay, so what about a spray vs gel (same Alcohol %)? I would be inclined to  believe that the spray would cover more surface area on the hands but does it possibly evaporate too quickly as spray whereas a gel would be less volatile?

    Any ideas?
  • BelassiBelassi Member
    Yes. The reason why gel is used is to slow the evaporation of the alcohol and allow effective virus killing.
    Cosmetic Brand Creation. Concept to name to IMPI search to logo and brand registration. In-house graphic design inc. Pantone specs. Cosmetic label and box design & graphics.
  • FekherFekher Member, Professional Chemist
    @Cafe33 World Health Organisation WHO proposed spray alcoholic product so for sure it is the effective product, going to gel may it reduce evaporation however it is difficult to have 75% or 80 % alcoholic gel.
     As conclusion as professional we must follow the certified formulation which is spray form and leave anything else.

  • AgateAgate Member
    edited March 23
    There seems to be some confusion around that gel = pump and liquid = spray, but this is wrong. Liquid sanitizers are not to be sprayed (for use on hands), as Belassi said you cannot apply enough and it will just evaporate too quickly. Liquid sanitizers are used in the exact same way as gel sanitizers. You may just need to use a bit more because you need a good amount for your hands to stay wet for long enough, and some will drip if you use enough. If you can't stop it from dripping, you're doing it right. If your hands aren't dripping with liquid sanitizer, you're probably not using enough.

    So just pour or pump ~3ml of liquid into one hand, and then do the WHO handrub steps: https://www.youtube.com/watch?v=ZnSjFr6J9HI Proper application is as important as the right product!
  • FekherFekher Member, Professional Chemist
    @Agate really interesting view about proper application, thanks for it. 
  • AgateAgate Member
    @Fekher Hope it helps :smile:
  • amitvedakaramitvedakar Member
    edited March 24
    one formula

    Each 100 Gms. contains :

    2-Propanol                                                      45 Gms.

    1- Propanol                                                     30 Gms.

    Macetronium ethylsulphate                                  0.2 Gms.

    (Ethyl hexadecyl dimethyl Ammonium ethyl sulfate)

    Purified Water                          Q.S.

    This is  not cosmetic.  alcohol percentage is around 90%v/v.
    what is the role of Macetronium ethylsulphate ?
  • lmoscalmosca Member
    @amitvedakar, all long chain quaternary ammonium salts are moderate antiseptics (think about cetrimonium, or benzalkonium). 
    They mainly operate by cell lysis and exhibiting some surfactant activity (albeit they are used at lower concentrations than you would if you'd use them as surfactants or emulsifiers).
    They work best against bacterial, amoebal, algal, and fungal contamination. They can be active against some viruses, especially when combined with other antiseptics, however, they are not recommended for gram-negative bacteria.

  • FekherFekher Member, Professional Chemist
    edited March 24
    @Agate sure it helps 😊. 
  • Thank You @lmosca
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