What are the possible solvents for ketoconazole apart from dmso?


  • try in Acid
  • It dissolves in acid.
    However I noticed that the solution changes color almost immediately like an oxidation reaction or something. Could it be degrading? Which antioxidant can help prevent this? Finally, can this (acid) affect the concentration of ketoconazole in a formulation over time? @amitvedakar ;
  • after dissolving immediate dilute it & add to mix. be sure final product pH to near 6
  • OK. Thanks
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