Chlorhexidine Digluconate Gel based

KingstoneKingstone Member
edited October 2019 in Formulating
Hi everyone,

Need to know your recommendations for the best Rehodology modifier to get Gel based like carbomer for Chlorhexidine Digluconate 0.2% and Ethanol 70%. 

Thx

Comments

  • PharmaPharma Member, Pharmacist
    For 70% ethanol, only PVP comes to my mind (though my mind isn't working properly, it's been a long day at work).
  • Bill_TogeBill_Toge Member, Professional Chemist
    try hydroxypropyl cellulose
    UK based formulation chemist. Strongest subjects: hair styling, hair bleaches, hair dyes (oxidative and non-oxidative) I know some stuff about: EU regulations, emulsions (O/W and W/O), toothpaste, mouthwash, shampoos, other toiletries
  • Chemist77Chemist77 Member, PCF student
    Agree with @Bill_Toge, I have used HPMC though and it came out pretty nice. But comparatively still on lower side of viscosity. I tried Methocel 40-202, you can try 40-101 grade which has higher viscous.  But mine was alcohol free with either benzalkonium chloride or CHG. 
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