Lactic Acid Stability

I am having issue with the Lactic acid during stability study. While running the HPLC method %LA tends to increase in the 40C sample (sometimes out of spec). Is this normal? Is there any other method to test for LA in a formula that has multiple acids?   

Comments

  • Bill_TogeBill_Toge Member, Professional Chemist
    the most likely explanation is that water is evaporating from the 40 °C sample over time, causing the percentage of lactic acid relative to the whole formula to increase
    UK based formulation chemist. Strongest subjects: hair styling, hair bleaches, hair dyes (oxidative and non-oxidative) I know some stuff about: EU regulations, emulsions (O/W and W/O), toothpaste, mouthwash, shampoos, other toiletries
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