Home Cosmetic Science Talk Formulating Creatine monohydrate

  • Creatine monohydrate

    Posted by jemolian on March 11, 2019 at 8:43 am

    I would like to ask if Creatine monohydrate can be used in place of Creatine? 

    I wanted to buy Creatine from Ingredients To Die For, which seems that they are the only one selling it, but they take very long to process their order. 

    Herbnerd replied 4 years, 10 months ago 4 Members · 4 Replies
  • 4 Replies
  • pharma

    Member
    May 20, 2019 at 12:29 pm
    In my experience, most people don’t even know the difference nor care that there is a slight one (even in scientific publications!).
    Most creatine sold is actually creatine monohydrate ;) . Once you put anhydrous creatine in water it will “hydrate”, resulting in the exact same thing if you consider the slight difference in molecular weight of the two.
    I got my creatine from one of the many “body-building webshops”… again, most sell monohydrate even if that’s nowhere mentioned.
  • gunther

    Member
    May 20, 2019 at 8:11 pm

    While some studies suggest that creating works for aged skin,
    as far as I know, creatine slowly degrades in water solution.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080578/
    https://www.ncbi.nlm.nih.gov/pubmed/19635041
    https://www.academia.edu/6026552/Effect_of_water_activity_and_temperature_on_the_stability_of_creatine_during_storage_Effect_of_water_activity_on_creatine_stability

    A creatine salt like Creatine HCl or Creatine citrate (which you can make by reacting creatine monohydrate with dilute HCl or citric acid yourself), might be a bit more resistant to degradation.

  • pharma

    Member
    May 20, 2019 at 8:16 pm

    Or use creatine ethyl ester hydrochloride or creatinol-O-phosphate ;) .

  • Herbnerd

    Member
    May 20, 2019 at 10:53 pm

    Creatine and creatine monohydrate are essentially the same thing. One is anhydrous the other is hydrated. Unless you are using this in a dry powder, it isn’t going to make any difference.

    Even if you do use it in a powder, anhydrous will turn to monohydrate quickly enough. It is a fairly hygroscopic material

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