Suspending actives in anhydrous formula

Unknown Member
in Formulating
 Hi there 
I'm currently working on a an anhydrous tanning oil formula and I'm curious if there's any way to suspend water soluble actives within formula while still maintaining its liquid state? Is there a way to keep the formula as a liquid oil (not a lotion) and incorporate water soluble actives??

Thank you!
Tagged:

Comments

  • DRBOB@VERDIENT.BIZDRBOB@VERDIENT.BIZ Member
    By suspend assume you mean solid actives and answer is no  as Stokes Law (settling) like sand in water will come into play sooner or later.A nano dispersion may work.
  • DFXDFX Member
    It's possible.
    But you need special dispersants and rheology modifiers. Also you have to make your particles as small as possible. 90%<10 micron (better 5 micron).
  • DRBOB@VERDIENT.BIZDRBOB@VERDIENT.BIZ Member
    problem is as particles become smaller Thermodynamic instability via Oswald Ripening(OR) takes over gradually leading to sedimentation via Crystal growth,micro size you may stand a chance with polymeric stabilizer that does not increase viscosity of oil.I don't know of any but even still total prevention of OR at the solid/liquid interface is unlikely.
  • DFXDFX Member
    edited September 2017
    No one said it will be easy.
    In my portfolio there is 1 commercial product with 4% a.i. in corn oil. Particle size is 90%<3 micron.
    3 years stable at RT. 6 months stable at +40 and -30C stable.
    So, It's possible
Sign In or Register to comment.