15% Azelaic serum

Hello chemist , I am trying to make an acne control and hyperpigmentation removal serum . Below is my formular , is it good ? 

Distilled water 
propylene glycol 15% 
Azelaic acid 15%
Aloe Vera juice 
hyaluronic acid 
niacinamide 5%
glycerine 
Xanthan gum 
licorice extract 
liquid germall 

Comments

  • PharmaPharma Member, Pharmacist
    Did you try to make/use it?
    There's a good discussion about said topic here somewhere. Keep in mind that you can't dissolve 15% azelaic acid without turning it into an effectless salt.
  • @Pharma i am trying to make it , and concerning the azelaic acid , I am going to dissolve it with the propylene glycol 
  • Bill_TogeBill_Toge Member, Professional Chemist
    edited August 3
    azelaic acid is not very soluble in anything - your best bet is to make the product an O/W emulsion with a very polar oil (e.g. a salicylate ester) as the oil phase
    UK based formulation chemist. Strongest subjects: hair styling, hair bleaches, hair dyes (oxidative and non-oxidative) I know some stuff about: EU regulations, emulsions (O/W and W/O), toothpaste, mouthwash, shampoos, other toiletries
  • JaycetowwwJaycetowww Member
    edited August 5
    Bill_Toge said:

    azelaic acid is not very soluble in anything - your best bet is to make the product an O/W emulsion with a very polar oil (e.g. a salicylate ester) as the oil phase 
    I can dissolve it with my propylene glycol
Sign In or Register to comment.