Home Cosmetic Science Talk Formulating General pKa measurement

  • pKa measurement

    Posted by Shams on February 24, 2022 at 11:07 pm

    Hi everyone,
    we are formulating some chemical peels using salicylic acid and lactic acid . These are only sold in professional clinics.
    One of our clinics asked to know the pKa of our peels.
    We have the pH set at 2.00 - 3.00.
    Can someone please help out how to measure the pka from pH?

    TIA

    Mayday replied 2 years, 1 month ago 2 Members · 1 Reply
  • 1 Reply
  • Mayday

    Member
    February 25, 2022 at 12:09 am

    pKa is mathematically derived from the Ka, or the acid dissociation constant. It doesn’t make any sense for your overall formulation to have a pKa, since that is used to describe the strength of a single acid in solution. There may be a miscommunication as to what information they want about your formula.

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