Home Cosmetic Science Talk Formulating Does dermosoft 1388 need a solubilizer in a water-based product?

  • Does dermosoft 1388 need a solubilizer in a water-based product?

    Posted by grapefruit22 on January 20, 2022 at 10:39 am

    Hi, 
    I’m looking for a preservative system for water-based product. I plan to use:
    - Sodium Levulinate & Sodium Anisate
    - 5% Propanediol
    - Phytic Acid
    Dehydroacetic Acid
    Package: glass bottle with a dropper
    pH: 5,3-5,5

    Recently we have checked Sodium Levulinate (and) Sodium Anisate powder blend, and there was an issue with solubility: after lowering pH to 5,5 dilution was not clear, it was white with precipitation.
    That’s why I’m wondering about dermosoft 1388. When dissolved in water at a concentration of 4%, dilution is clear and there is no problem with lowering the pH to 5.5. But according to manufacturer in water-based product only 2,5% dermosoft 1388 can be used and with a solubilizer. On the other hand, I saw water-based products, with Sodium Levulinate with Sodium Anisate as the only preservative.
    Does anyone have experience with using dermosoft 1388 without solubilizer in water-based product?  At what concentration?

    grapefruit22 replied 2 years, 2 months ago 3 Members · 3 Replies
  • 3 Replies
  • markbroussard

    Member
    January 20, 2022 at 3:14 pm

    @grapefruit22

    Dermosoft 1388 is Glycerin, Water, Sodium Anisate, Sodium Levulinate and you generally use it at 3% or so.  No solubility issues.

    If you have access to Sodium Levulinate (and) Sodium Anisate powder blend, I would check on the compositional analysis of Dermosoft 1388 and use the same amount in a 50/50 blend of Glyerin and Water.  You may need to use heat to get it into solution.

  • suswang8

    Member
    January 22, 2022 at 6:26 pm

    A solubolizer is not required, but can I ask why you’re trying to use it as a concentration of 4pct?

  • grapefruit22

    Member
    January 24, 2022 at 5:17 pm

    suswang8 said:

    A solubolizer is not required, but can I ask why you’re trying to use it as a concentration of 4pct?

    Manufacturer recommends 3-4%, do you think it’s too much?

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