“What does a formulation scientist do every day?”

This was a question I received in an email from someone who was doing some research about different chemist careers. And if this person wanted to know about it, it makes sense that some of you might be wondering the same thing. So, here it is, 75 things that a formulation scientist or cosmetic chemist might do on any given work day, conveniently presented in four categories.

Cosmetic product development

Create formulas
Gather raw materials
Get equipment for making batches
Make batches
Restock lab supplies
Keep notes in notebook
Write experimental results in notebook
Clean glassware and lab
Research formulation topics
Generate new product ideas
Create prototypes
Create dye solutions for color matching
Make samples for marketing
Supervise / make batches for home use tests
Supervise first production batches
Solve stability problems
Generate test ideas to substantiate claims
Figure out ways to make formulas less expensive
Attend focus groups
Participate in brainstorming meetings
Review product label copy
Assist in writing product concepts
Present new technologies to non-scientists

Cosmetic product testing

Take pH readings
Take viscosity readings
Fill and label glass and plastic bottles
Wash & comb hair tresses
Color matching
Bleach and color hair tresses
Conduct foam tests
Run stability tests
Conduct skin moisturization tests
Run project specific, customized tests
Try formula prototypes
View samples under a microscope
Observe salon tests
Conduct odor tests
Participate in product panel testing
Get samples for testing
Evaluate competitive products

Personal Training

Read trade journals
Read Chemists Corner and other useful blogs in your RSS reader
Attend meetings with suppliers
Go to SCC meetings
Go to industry trade shows
Take continuing education courses
Attend conferences
Review latest patents
Listen to podcasts like the Chemists Corner podcast
Read industry text books
Take online training courses
Pursue an advanced degree in cosmetic science

Business stuff

Respond to emails
Create presentations
Attend corporate meetings
Attend project planning meetings
Respond to phone calls
Do desk side interviews with beauty editors
Conduct training sessions for non-scientists
Write business travel reports
Fill out expense reports
Write monthly reports
Go to office celebrations
Engage in “water-cooler” chat with co-workers
Write memos
Sign and review contracts
Give instruction to people who report to you
Meet with your boss to update them on your progress
Interview candidates
Entertain kids during Bring Your Kid to Work week
Keep track of project progress
Engage in debates with regulatory & legal departments
Write patent applications
Write employee reviews

Whew! My brain is fried and I might be able to go on, but I think I covered practically everything I did as a cosmetic chemist.

Is there anything we missed? Leave a comment below

Here’s the biggest difference between what you experienced in your college organic chemistry lab versus a cosmetic formulation lab. In an organic lab, you mix chemicals together and hope something happens. Ideally, you get a chemical reaction you expect. As a formulating chemist, you mix chemicals together and hope nothing happens. Cosmetics are mixtures of chemicals that mostly aren’t supposed to react with each other.

Unfortunately, they often do react (or otherwise change) so you need to test your formulas to see how long they will last. This is called Stability Testing and is something a cosmetic scientist spend much of her time doing. In this post, we’ll give a brief description of the test and suggest when, why and how it should be done.

What is stability testing?

Stability testing is simply an experiment in which you create a batch of your formula and put samples of it at different environmental conditions for a set period of time. These conditions vary in temperature and light levels and are meant to simulate what will happen to the product during its life cycle.

At select intervals you evaluate your samples for various physical, chemical and performance characteristics to see how they have changed. If the changes are minimal according to your company standards, then your formula is said to have “passed” stability testing. This means you can have confident that when the formula is shipped to stores and ultimately customers, it will still be as good as when it was first manufactured.

The underlying assumption in stability testing is that increasing storage temperature speeds up any aging reactions that will occur. A handy rule of thumb is that a sample stored at 45C for 8 weeks is equivalent to one that is stored at room temperature for one year. This isn’t an exact predictor, but is good enough for the purposes of cosmetic products.

A sample stored at 45C for 8 weeks is equivalent to one stored at room temperature for a year

When do you perform stability testing?

Since you’ll be making hundreds or thousands of prototypes during your career, it won’t be practical to run a stability test on all of them. You’ll also find that changes happen so rapidly at your company, you won’t have time to properly test many of your formulas. But there are times when you need to do stability testing. Here is a short list of some of the most important times to conduct a stability test.

1. New prototypes – Whenever you make a new formula and are satisfied with the way it performs, you’ll want to do a stability test to ensure that it will stay together. Don’t bother testing all your prototypes, just the ones that work the way you want.

2. New raw materials – Whenever you have to change the fragrance, color, or other raw material in a formula, you’ll have to do a stability test to make sure there aren’t unacceptable changes. Also, when you have a new raw material source (or supplier) you’ll want to run a test.

3. New manufacturing procedure – Manufacturing is always trying to find faster ways to make formulas. This often means they change some order of addition or shorten mixing time. Whenever changes like these happen, it could affect your formula. Run a stability test to see if the change is acceptable.

4. New packaging – Cosmetic products change their look almost yearly so packaging is constantly being modified. Whenever you get a new package, you’ll have to determine if the formula continues to be compatible. Stability testing helps ensure that it is.

How do you stability test a cosmetic?

There are no set rules on how you must conduct a stability test for cosmetic products. Of course, for cosmetic OTC products like sunscreens, AP/DO, or dandruff shampoos the FDA has specific stability test requirements that you have to follow. See the FDA website for more information.

Here is a basic format you can follow for conducting a cosmetic formula stability test.

Step 1 – Make your batch. Calculate how much to make based on the number of samples you’ll be using for the test. It’s a good idea to make 30-40% more than you think you’ll need.

Step 2 – Fill your samples. Ideally, you’ll have the correct packaging but don’t count on it. When appropriate, fill glass jars with the product along with the finished package. In stability testing, you want to do both glass and packaging if possible. The number of samples depends on how much testing your doing but at minimum you should have 2 samples for each storage condition.

Step 3 – Take initial readings. Once you have a sample filled test it for all the characteristics you’re going to evaluate later. The exact tests depend on the product but minimally you’ll want to record notes about the appearance, color and fragrance. You’ll also want to take pH and viscosity readings. For aerosol products you will test spray patterns.

Step 4 – Put samples at different conditions. Stability testing requires different temperature and light conditions. Some standard temperatures include 50C, 45C, 37C, 25C (RT), and 4C. You’ll also want to conduct a freeze/thaw stability test which involves cycling your product through 24 hours of freezing then 24 hours of thawing. Different lighting conditions involve a fluorescent light box and a natural light box (to simulate sunlight).

Step 5 – Evaluate the product. Samples should be evaluated at the following intervals. 2 weeks, 4 weeks, 8 weeks, 12 weeks, and 52 weeks. Only the RT, 37C and 4C samples will be evaluated after one year. The highest temperature samples and the light exposed samples only need to be evaluated for the first three test intervals. The evaluation tests should be the same ones you conducted when taking your initial readings.

Step 6 – Determine stability. After 8 weeks you can confidently decide whether your formula is stable or not. Nearly all products will exhibit some change so it will be up to you (and your boss) to decide whether the product passed or not.

Early in your career, stability testing will be one of the most common activities you’ll do. If you can create a system that you consistently follow, you’ll avoid burn-out and be able to confidently communicate when a product is appropriate to launch.

How does this compare to your company’s stability procedure? Leave a comment and let the rest of the cosmetic chemists here know.