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  • In Switzerland, health authorities provide everything online. It has a stupid name if you want to find it using Google: ElViS. EDIT: Forgot to mention, you have to create an account and that's something usually reserved to registered health professi…
  • Vitamin E oil is commonly tocopherol acetate, and that's not natural ;) . You completely lack any preservation (tocopherol acetate ain't an antioxidant). That thing will 'rot' like nothing. @ngarayeva001 Seun is from Nigeria, his/her (?) hair probab…
  • (Quote) 
First, I hope that you're really that open to all feedback since my concern with your formulation is just one: Hopefully, your chemistry professor doesn't read your post! There is no such thing as sodium laurel sulfate. The product …
  • (Quote) 
Kojic dipalmitate will be degraded by sodium hydroxide to kojic acid sodium salt and sodium palmitate and madecassoside will be split in half resulting in free triterpene and a sugar chain.What is 6 copolymer?HEC and hydroxypropyl g…
  • You could try hydroxypropyl cellulose, ethyl cellulose, or hydroxyethyl cellulose. They should be soluble in 1,3-propanediol although, quite frankly, I'm not sure if they also thicken, let alone gel, that solvent without any water present.Or use a h…
  • @Belassi : Thanks!No fishy smell or do you mask it?
  • Correct, it's best done before. If you want to measure afterwards, you'd have to break the emulsion and separate the water phase for proper pH measurements. This may be done for example by centrifugation, addition of more oil, or mixing with acetone…
  • In order to really reduce fat, you'd have to use something like a decoupler of oxidative phosphorylation in mitochondria such as 2,4-dinitrophenol. This compound has been sold as a weight loss drug some 90 years ago... until a bit too many folks die…
  • @Belassi : That's really interesting. Are you using it above or below 1%?@ngarayeva001 : Absolute solubility of EDTA is governed by pH, only speed of solubilisation depends on the used salt or free acid. As long as you have the right pH, you can nea…
  • What if only water and glycerine are above 1%? It's a serum and there's nothing in there which requires more than 1% (except for water)... if not directly before EDTA, I'd guess the 1% line would be directly after EDTA and before DMAE ;) . A propos …
  • Ethanol and glycerine preserve mainly by reducing water activity. Hence, % of water counts and ethanol and glycerine show an additive effect.Let's assume that 40% glycerol results in full preservation (no microbial growth), 20% would therefore be ha…
  • Honestly, I just write some meaningless stuff but add a bunch of hyperbolic words. This lets me look superconductively smart although I have no idea what the heck they mean. :smiley:
  • 1,4-Benzoquinone
  • I don't know, I just happened to stumble upon these recently (with stumble I mean read, not buy nor try). Seems as if gels obtained therewith are always crystal clear... but that's just regurgitating what advertisement claims.
  • @hugi28 Why 500 Da? Are you referring to the Lipinski rule of five?This rule applies mainly to drug bioavailability by oral route and not necessarily to skin penetration, let alone effectiveness of cosmetic ingredients which mostly act on the skin a…
  • From what I understand, pickering emulsions are less forgiving to composition changes (= less flexibility such as last-minute adaptations), they are micellar emulsions (= spherical droplets in a continuous phase), have a small particle size with nar…
  • No, these are not the same. Arbutin is more hydrophilic than deoxyarbutin and alos more likely to be cleaved to hydroquinone by glucosidase enzymes.
  • The effect is not limited to a distinct chemical structure but mostly to a lipophilic, non-ionic structure (of preservative and emulsifier), surfactant-like behaviour, and preservative/emulsifier interactions (which is a result of the former two pro…
  • Dibutyl ethylhexanoyl glutamide or dibutyl lauroyl glutamide
  • It's likely in there for the only reason it's commonly used, as chelate to boost preservation (I mean chemical and biological preservation of the product, not preservation of the user :smiley: ).
  • (Quote) 
Reason has it that this would mean it becomes alkaline since the acid (H2O2) decomposes ;) .I don't have a definite answer but a guess: It might be stabilisers which causes the effect. H2O2 is often stabilised with a small amount ph…
  • Glycerol, sorbitol or xylitol may work at proper concentration by reducing water activity. As a rule of thumbs, 40% glycerol should be stable for years, 30% for several months. 20% ethanol is sufficient to stop bacteria from growing although it won'…
  • Is it a ready-to-use formula or a concentrate?A concentrate may be preserved with ethanol.I think that pH 10 is a bit too harsh for the mouth...
  • You're probably producing cocoyl glycine which is no longer a high HLB anionic sufactant but a low HLB non-ionic one which also lost most of its surfactancy.At a rough estimate, this starts happening at a pH below ~4.5 (really starting to get proble…
  • The amount of iodine (iodide, to be precise) is minuscule and won't disturb as long as you're not using it in an oxidising formula (e.g. containing hydrogen peroxide or benzoyl peroxide).Sea salt contains a lot more than just iodide and it's frequen…
  • Depends on what you want to solubilise where ;) .For what does the abbreviation MPG and DPG stand for?
  • Dehydroacetic acid was/is one of the first 'alternative' preservatives though it's a quite old compound which just sounds natural but isn't and hence is mainly good for 'free from' claims. It's somewhat outdated due to too poor performance compared …
  • From what I've read, they're super fancy and very stable because they're a bit like microencapsulated oil droplets which can neither fuse/coalesce nor undergo Ostwald ripening.
  • pH 5.5 ain't bad. I thought that maybe you've got something around 7 and hence the many preservatives (though some of which only work at <5.5).Personally, I wouldn't feel comfortable with that many preservatives. The weakest but also most prone t…
  • Uppps, I just realised that I wrote 1,3-botanediol instead of 1,3-butanediol ;( .I wouldn't use either of the two.1,3-butanediol might work as nutrient supplement and sure, it does what similar compounds do but I'd rather go with one which also boos…
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