On the other hand, I once went on a job interview where the only equipment in the lab was an ancient overhead stirrer, a hot plate, and a kitchen balance in a room the size of a small closet. I didn't take that job - making do on a small budget is o…
Honestly, even though I'd appreciate the business (and I've designed several labs), I think you'd be better off (and have a happier chemist) if you involved them in at least some of the design and equipment choices.
No matter how you choose to proc…
Like a lot of things, you can put in the time to find out yourself, or you can hire a consultant. Free information is sometimes worth only what you've paid for it.
I like coil impellers for a number of reasons, not least of which is that it's difficult to break a glass beaker with one, no matter how fast it's going.
https://www.thomassci.com/Equipment/Overhead-Stirrers/_/2f648f8a-e711-40ad-8146-ce7cfb41744d
What I described is the highest level of method validation, as I've had it explained to me, in the context of "why does this cost so much?" How much, if any, validation is done is up to each individual manufacturer.
Everyone's tolerance f…
Perry's right. Unrefined shea smells bad. You can either use refined shea to get rid of the odor, or you can use fragrance to mask the odor, or you can choose to live with the odor, but there aren't any other choices.
Some CMO's, and even some consultants, may offer their formulating services without conveying ownership of the formula. (This isn't really IP, since no patents are involved) Doing this is usually much cheaper than owning the formula, but it locks yo…
As I understand it, method validation is a series of API assays, using placebos/knock-outs, which make sure that your formula specifically can be tested and produce accurate assay results. For example, using only 1 API (for simplicity), ideally you'…
It's complicated, but the short version is that method validation is what proves that your API assay test is accurate for your specific formula. It should be done every time a significant formulation change is made. Without it, you don't really have…
Unfortunately, "light and non-greasy oil" is diametrically opposed to "lasting moisturization through out the day". You can have one, but not the other, or you can strike a balance between the two, but you can't have both.
It ma…
If, for example, it's this or something similar to this:
https://www.etsy.com/listing/195354106/organic-hands-cream-honey-and-aloe-honey
Materials: raw honey, aloe vera, olive oil, almond oil, geranium blossoms water, rosemary, grapefruit
There a…
The major point I was trying to make applies to color and any other product. In my experience, scale-ups start to fail when there's too much difference between steps. Usually, the geometry/rheology/energy input of the systems is too far from being …
When dispersing pigments, you want to use the thickest mixture that your mixers can handle. Particle-to-particle interaction can help improve the dispersion.
If you were buying new equipment, a ball mill, 3-roll mill or colloid mill would be ideal.…
100 gallons isn't really a production size - it's closer to a large pilot batch. The answer to this will be distorted by the need to make such a small batch.
Sometimes, the treatments are so sticky that the pigments clump up. Try mixing them dry in a blender together with the nylon before adding them to your batch. Also, an IKA homogenizer isn't the best option for dispersing pigments.
I agree with Bill. I'd suspect that the plastic mix is inconsistent, and that the solvent is probably leaching out some of the plasticizer, leading to the plastic cracking in areas of high stress/low plasticizer - but I'd need it tested to confirm.
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