Will surfactant homogenize with Hyaluronic Acid?

Don’t ask me my reason(s), but if I were to take a Hyaluronic Acid solution/stock (water + hyaluronic acid only) and add a surfactant into it, would the surfactant be able to homogenize with the HA stock and stay blended, or would this combination just separate?


  • Best way is to just try it out yourself and see what happens. Nobody can say much without you providing information on the hyaluronic solution and which surfactant and what you are trying to achieve.
    Cosmetic Product Development
    Sussex Research Laboratories Inc.
  • PerryPerry Administrator, Professional Chemist
    I'm not sure you are using the term "homogenize" correctly.  Can you explain more what you mean?

    Hyaluronic Acid is water soluble so your question doesn't exactly make sense.
  • @Perry I just mean are they going to combine together as one, or would they separate. Sorry if it’s the incorrect word usage.

    @JonahRay Just water with either 0.5% or 1% Hyaluronic Acid and 4% sodium cocoyl glycinate (25% active matter). 

  • PerryPerry Administrator, Professional Chemist
    The ultimate answer to your question is as @JonahRay says, make it and see. The %'s you said seem reasonable enough.

    But in general, both HA and Sodium Cocoyl Glycinate are water soluble so unless you are adding concentrations above the solubility limit or you are forming an insoluble salt, there shouldn't be a problem.
  • Thank you @Perry
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