Hazardous Ceteareth-25's vapors?

Hello everyone

I have a question about the hot handling of c-25 (c-25 from KLK oleo kolb) , I have been developing a water-soluble pomade with different textures or good, different consistencies. They have been very small samples that I have elaborated (this with the obejtivo of not expending the reagents)

I do not have a laboratory heating plate to heat the c-25 (in order to mix it with the other phase) so I have been heating it to the direct flame, controlling that it does not reach its boiling point or isn't overheat

But nonetheless this sometimes creates a vapors (and a somewhat unpleasant smell) to which I would like to ask:

Are these vapors toxic or do they pose a health risk? (In order to take the appropriate measures, well apart from buying a heating plate)

Thanks so much 


  • Using direct flame in cosmetic chemistry is not something you ever want to do. First, many of the compounds we use are either flammable or highly inflammable. My own lab for instance, smells of fragrances, despite the fact I use glass bottles. Just a glance at the fragrance shelving makes me cringe and think that I really must upgrade my fire precautions. The thought of using an open flame would have me running out the door.
    Secondly, heating like that is highly uneven and degrades the compounds which is exactly why you reported an unpleasant smell. As a result your experiments are a waste of material because it has been degraded by the overheating.
    It is rare to need >100C in cosmetic chemistry and a small water bath and electric hotplate - get the type with a thermostat - can provide that. For heating batches that contain water, use a microwave oven.
    Cosmetic Brand Creation. Concept to name to IMPI search to logo and brand registration. In-house graphic design inc. Pantone specs. Cosmetic label and box design & graphics.
  • Laboratory Heating plates are very cheap. I have one in my house. Sometimes I used it for cooking foods. Haha

    No, but seriously, @Belassi 's right, unless you want to start a fire.
  • @Belassi @Lainee

    I know and it is a bad idea use the direct flame heating since there is no total temperature control and there may be a combustion, so I have stopped everything until I buy a heating plate

    But I would like to know if the vapors emitted by the Ceteareth -25 pose a health risk
  • @Rebelgreaser66 where do you put your mixture? 

    You should use a solubilizer like PEG-40 Hydrogenated Castor Oil or PEG-7 Glyceryl Cocoate instead of heating. Both are available worldwide so no excuse.
  • Bill_TogeBill_Toge Member, Professional Chemist
    ceteareth-25 has negligible vapour pressure unless you heat it well over 100°C, or spill it on a hot surface
    UK based formulation chemist. Strongest subjects: hair styling, hair bleaches, hair dyes (oxidative and non-oxidative) I know some stuff about: EU regulations, emulsions (O/W and W/O), toothpaste, mouthwash, shampoos, other toiletries
  • @Lainee @Bill_Toge
    yes, i use PEG-40 Hydrogenated Castor Oil or PEG-7 Glyceryl Cocoate and anyway I should heat the ceteareth apart

    My main question is whether these vapors emitted by the C-25 represent any health risk or are toxic
  • I melt substances au bain marie, with a simple bottle warmer. It's cheap, it can hold my 250 ml beakers and it has a max of about 80C, which is high enough.

    About the toxicity of ceteareth-25, have you read the safety data sheet?
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