Suppository formulation using PEGs

Hello all,  I'm wondering if anyone here has experience in formulating suppository bases using PEGs. I've found some formulas that use use PEG 3350 as a base and I would like to know if that won't cause a laxative effect. Thank you! 


  • GuntherGunther Member
    This is a pharmaceutical product, even if it were approved to be sold OTC,
    this is something only a pharmaceutical chemist should formulate, not an amateur.

  • MarleyMarley Member
    Please only helpful responses, thank you! 
  • GuntherGunther Member
    This is as useful a response as it can get
    FDA Regulations clearly state that you'd need a licensed pharmacist.
    So you'd better find one and ask him or her.
    Don't ask in an Internet board (that's focused on cosmetics, not pharma, by the way)

  • MarleyMarley Member
    edited May 2019
    Thank you @Gunther, I'm working with a laboratory on this formulation, just wanted to see if anyone on this forum had any experience working with PEG 3350 because none of us have worked with it before. 
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