povidone iodine 10% solution for wounds — Cosmetic Science Talk

povidone iodine 10% solution for wounds

Hello There, I am a pharmacist and i intend to start small business to produce some products,  one of them is Povidone Iodine 10 % solution - equal to BETADINE, I found this formula but it is not for industrial purposes as i think, it has a short shelf life about 3 months and not economically effective, Any body Can help by advise regard the formula??
I used : 

Povidone iodine powder

110 g

Sodium dihydrogen phosphate anhydrous

13.6 g

Citric acid monohydrate

8.8 g

Water

to 1000 ml

Comments

  • Well, what is the Betadine LOI? There's your start point.
    Design of anti-aging creams, gels, and serums; shampoos; and therapeutic cosmetics. In-house label and box design capability.
  • Betadine is povidone iodine solution 10%
  • As Belassi suggested, you should find some product references and check the list of ingredients (LOI).
    Here is what I found:
    Excipients: glycerol (glycerin), nonoxynol 9, citric acid anhydrous, disodium hydrogen phosphate, sodium hydroxide 10% solution (w / v) (for pH adjustment), purified water. 
  • Easy, you can find the LOI and mixing procedure in practical pharmacology book of the 3rd year of any medical college.
  • Talking about iodine. They painted me with some weird stuff when I was in the Cath Lab. After, I couldn't get it off for days and days. It was like a brown film stuck on to my skin, obviously contained iodine. They paint most of the patient with it during major surgery.
    Design of anti-aging creams, gels, and serums; shampoos; and therapeutic cosmetics. In-house label and box design capability.
  • @Belassi that is 3MDuraPrep antiseptic surgical solution, its usually used to sterilize the surgical site, mainly skin. As you described, its creates a water resistant and wash off resistant film that can last for 2-3 days. 
  • Isn't that stuff povidone iodine and PVA?

    UK based, Over 20 years in Toiletries, After a 5 year sabbatical doing cleaning products, back in the land of Personal Care
  • or even PVP
    UK based, Over 20 years in Toiletries, After a 5 year sabbatical doing cleaning products, back in the land of Personal Care
  • It's not really clear to me what kind of help you need?
  • My friend Zaidjeber, in pharmaceutical book it is merely a formula for lab practice not industrial formulation. Do you have any recommendations?
    Belassi you are right. I think the formula may contain xanthan gum so it will form a film on skin.
    Duncan yes  it is.
    Doreen81 what i need to know is how to convert this lab formula to an economical long shelf life formula, especially it is for wound disinfection purposes.
    So guys how doyou suggest to proceed?
  • Just for starters I doubt the formula you presented. It contains no alcohol. I don't believe iodine is water-soluble. The stuff they painted me with was freezing cold, evaporated very fast, and I could smell the ethyl alcohol. 
    Design of anti-aging creams, gels, and serums; shampoos; and therapeutic cosmetics. In-house label and box design capability.
  • povidone iodine is water soluble 
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