Polysorbate 20 Alternative

To mix oil with water, I will be needing a solubilizer. Polysorbate is the best choice. However, it is found to be a carcinogen. Can you recommend an organic/natural solubilizer alternative in liquid form?


  • What Journal-documentation  and clinical tests are you basing this on? Cremaphor BASF  eo adducts of hydrogenated castor oil
  • MicroformulationMicroformulation Member, Professional Chemist
    edited September 2017
    The belief that Polysorbate and other ethoxylated compounds are carcinogens is somewhat outdated and really falls more properly under fear mongering. Before 1,4 Dioxane was identified as a carcinogen, ethoxylated compounds had high levels of 1,4 Dioxane. However, in response to this, there are new processes which greatly reduce the presence to very low ppm ranges. Even the State of California now has an acceptable range under the Prop 65 limitations.

    However, like many raw materials, the marketing bias was already out there and it is perpetuated by those with a surface level familiarity with the issue. But, like many raw materials, there is little return in arguing and most importantly there are numerous alternatives. This would be a vastly different response if it was 15 years ago and the alternatives were not available.

    PEG-40 Hydrogenated Castor oil also shares the same issue (note that many Cosmetic lines assert no PEG's) for the same reason as Polysorbate. The most universally accepted alternatives are APG derivatives and I personally like the Poly Sugamulse D6 from Colonial Chemical. http://www.colonialchem.com/poly-sugamulse-d6/

    markfuller@microformulation.com Microformulation.com Microformulation Cosmetic Consulting provides Custom Formulations for both large Commercial accounts as well as smaller entrepreneurs. We can provide Naturally compliant Formulations under the NSF, NPA, Whole Foods and USDA Organic Certifications. BS.Pharm Albany College of Pharmacy, Union University.
  • PEG-7 Glyceryl Cocoate.
    PEG-40 Hydrogenated Castor Oil.
    Tegosoft PC 41.
  • decyl glucoside
  • durosoft theres 2 types
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