SOLUBILIZE 5% CAFFEIN IN AQUOUS MEDIUM - Cosmetic Science Talk

SOLUBILIZE 5% CAFFEIN IN AQUOUS MEDIUM

Hi everyone!
I hope someone can help me.... :) I am reformulating a 5% caffein aquous solution cause the Sodium benzoate restriction use (0,5%). Has anyone experience with this or know any book that can help managing it?

Thank you!!!

Comments

  • Caffeine is only soluble in room temp water to 2%. You haven't said how you got 5% to dissolve.
    Special interests: anti-aging creams, gels, and serums; sulphate-free shampoos; and therapeutic cosmetics.
  • We get it using 7% of sodium benzoate but then we realize it's not legal !!! So I don't know if there exist a combination of other ingredients that rise the caffein solubility.... I have checked the caffein's solubility in different solvents and it is said that dichloromethane is 0,532M (water 0,105M). But it's a cocktal for mesotherapy so I guess it could be toxic....isn't it?
  • edited March 30
    Exactly. I don't see a way you can get more than 2% into solution. Even then it's going to drop out if the storage temp drops very much, since it appears to be highly dependent on temp. You might consider the use of similar stimulants such as quinine. After checking this page there is no way I would want to be associated with the risks. 
    Special interests: anti-aging creams, gels, and serums; sulphate-free shampoos; and therapeutic cosmetics.
  • Is that 0.5% sodium benzoate figure absolute or does it apply to its use as a preservative?

    Either way, do you really need 5% caffeine in your product?

    Caffeine forms a water soluble complex with vanillin (1:1 equimolecular) and with niacinamide (1:1). You might want to consider those.
  • I ought to point out that the vanillin/caffeine complex is the subject of an obscure Japanese patent. There has been no attempt to expand the area of coverage so the patent only applies to Japan.

    Niacinamide/caffeine complexes were subject to patents but these are expired.
  • We were using sodium benzoate to solubilize caffein. Thank you very much for your contributions! I would have a go :)

  • Sorry this is an old thread but I have been looking into the topic myself and found this product which contains 5% caffeine:
    http://theordinary.com/product/rdn-caffeine-solution-5pct-egcg-30ml
    Can anyone weigh in on how they are getting such a high amount to dissolve safely? 

  • Look at the LOI: propanediol and Dimethyl isosorbide look kind of interesting...
    Special interests: anti-aging creams, gels, and serums; sulphate-free shampoos; and therapeutic cosmetics.
  • edited April 17
    It's intended for the skin but I'm toying with the idea of using it as a scalp serum to stimulate hair growth, having been unable to find an actual scalp product which doesn't have some irritating ingredient or other. How it will work for such an application I'm unsure, will have to try and determin whether it feels sticky. Anyway, I thought it may be of interest to the original poster.
Sign In or Register to comment.